Polyhexamethylene biguanide and its antimicrobial role in wound healing: A narrative review

MG Rippon, AA Rogers, K Ousey - Journal of wound care, 2023 - magonlinelibrary.com
A wound offers an ideal environment for the growth and proliferation of a variety of
microorganisms which, in some cases, may lead to localised or even systemic infections that …

[HTML][HTML] Biodiversity of skin microbiota as an important biomarker for wound healing

C Ersanli, A Tzora, C Voidarou, S Skoufos, DI Zeugolis… - Biology, 2023 - mdpi.com
Simple Summary Wounded skin can naturally be repaired by a mechanism called wound
healing. Human skin is a habitat of various pathogenic and commensal bacteria. While …

[HTML][HTML] The effects of rotating magnetic field and antiseptic on in vitro pathogenic biofilm and its milieu

D Ciecholewska-Juśko, A Żywicka, A Junka… - Scientific Reports, 2022 - nature.com
The application of various magnetic fields for boosting the efficacy of different antimicrobial
molecules or in the character of a self-reliant antimicrobial agent is considered a promising …

[HTML][HTML] The cross-linked bacterial cellulose impregnated with octenidine dihydrochloride-based antiseptic as an antibacterial dressing material for highly-exuding …

D Ciecholewska-Juśko, A Junka, K Fijałkowski - Microbiological Research, 2022 - Elsevier
The highly absorbent, antibacterial dressings with a sustained release of the antimicrobial
are considered necessary measures to counteract chronic wound biofilm-based infections …

[HTML][HTML] Culture Shock: An Investigation into the Tolerance of Pathogenic Biofilms to Antiseptics in Environments Resembling the Chronic Wound Milieu

J Paleczny, M Brożyna, B Dudek, A Woytoń… - International Journal of …, 2023 - mdpi.com
Credible assessment methods must be applied to evaluate antiseptics' in vitro activity
reliably. Studies indicate that the medium for biofilm culturing should resemble the …

[HTML][HTML] The chronic wound milieu changes essential oils' antibiofilm activity—an in vitro and larval model study

M Brożyna, B Dudek, W Kozłowska, K Malec… - Scientific Reports, 2024 - nature.com
Abstract Essential Oils (EOs) are currently being researched as potential antibiofilm agents
to combat infections related to chronic wound biofilms. As documented in the literature, EOs' …

[HTML][HTML] The Assessment of Activity of Antiseptic Agents against Biofilm of Staphylococcus aureus Measured with the Use of Processed Microscopic Images

G Krasowski, P Migdał, M Woroszyło… - International Journal of …, 2022 - mdpi.com
Staphylococcal biofilms are major causative factors of non-healing wound infections. Their
treatment algorithms recommend the use of locally applied antiseptic agents to counteract …

[HTML][HTML] In vitro activity of octenidine dihydrochloride-containing lozenges against biofilm-forming pathogens of oral cavity and throat

B Dudek, J Tymińska, P Szymczyk-Ziółkowska… - Applied Sciences, 2023 - mdpi.com
The disruption of the balance in the composition of oral and throat microbiota due to
overgrowth of infectious biofilms may lead not only to severe infections, but also to serious …

[HTML][HTML] The Medium Composition Impacts Staphylococcus aureus Biofilm Formation and Susceptibility to Antibiotics Applied in the Treatment of Bone Infections

J Paleczny, M Brożyna, R Dudek-Wicher… - International Journal of …, 2022 - mdpi.com
The biofilm-associated infections of bones are life-threatening diseases, requiring
application of dedicated antibiotics in order to counteract the tissue damage and spread of …

[HTML][HTML] Comparison of antibiofilm activity of low-concentrated hypochlorites vs polyhexanide-containing antiseptic

J Paleczny, AF Junka, P Krzyżek… - Frontiers in cellular …, 2023 - frontiersin.org
Chronic wound infection is highly associated with morbidity and endangers the patient's life.
Therefore, wound care products must have a potent antimicrobial and biofilm-eradicating …