Renalase was discovered as a protein synthesized by the kidney and secreted in blood
where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested …

Renalase is a~ 38 kDa flavin-adenine dinucleotide (FAD) domain-containing protein that
can function as a cytokine and an anomerase. It is emerging as a novel regulator of …

Background/Aims: Renalase, a novel flavoprotein expressed in the kidney and heart,
reduces renal tubular necrosis and apoptosis, which suggests that it might protect against …

Oxidative stress and inflammation have been demonstrated to be involved in the onset and
promotion of diabetic nephropathy (DN). Tanshinone IIA (Tan) possesses both antioxidant …

Background Contrast-induced nephropathy (CIN) is the third leading cause of hospital-
acquired acute renal failure. Oxidative stress, apoptosis and inflammation play crucial roles …

Chronic kidney disease is associated with higher risk of cardiovascular complication and
this interaction can lead to accelerated dysfunction in both organs. Renalase, a kidney …

Ischaemic preconditioning (IPC) attenuates acute kidney injury (AKI) from renal ischaemia
reperfusion. Renalase, an amine oxidase secreted by the proximal tubule, not only …

Objective Renalase, a novel secretory flavoprotein with amine oxidase activity, is secreted
into the blood by the kidneys and is hypothesized to participate in blood pressure (BP) …

Background Renalase is a kidney-origin monoamine oxidase which can degrade
catecholamines and regulate blood pressure and cardiovascular function. Although it has …

Background and objectives: Renalase, a monoamine oxidase derived from the kidney, can
degrade catecholamine (CA) and regulate blood pressure as well as cardiac function. To …