[HTML][HTML] SOX transcription factors as important regulators of neuronal and glial differentiation during nervous system development and adult neurogenesis
M Stevanovic, D Drakulic, A Lazic… - Frontiers in molecular …, 2021 - frontiersin.org
The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …
properties of both classical TFs and architectural components of chromatin. Since the …
The loci of evolution: how predictable is genetic evolution?
DL Stern, V Orgogozo - Evolution, 2008 - academic.oup.com
Is genetic evolution predictable? Evolutionary developmental biologists have argued that, at
least for morphological traits, the answer is a resounding yes. Most mutations causing …
least for morphological traits, the answer is a resounding yes. Most mutations causing …
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
T Wagner, J Wirth, J Meyer, B Zabel, M Held, J Zimmer… - Cell, 1994 - Elsevier
A human autosomal XY sex reversal locus, SRA1, associated with the skeletal malformation
syndrome campomelic dysplasia (CMPD1), has been placed at distal 17q. The SOX9 gene …
syndrome campomelic dysplasia (CMPD1), has been placed at distal 17q. The SOX9 gene …
SOX9 is a potent activator of the chondrocyte-specific enhancer of the proα1 (II) collagen gene
The identification of mutations in the SRY-related SOX9 gene in patients with campomelic
dysplasia, a severe skeletal malformation syndrome, and the abundant expression of Sox9 …
dysplasia, a severe skeletal malformation syndrome, and the abundant expression of Sox9 …
SOX9 directly regulates the type-ll collagen gene
DM Bell, KKH Leung, SC Wheatley, LJ Ng, S Zhou… - Nature …, 1997 - nature.com
Mutations in human SOX9 are associated with campomelic dysplasia (CD), characterised by
skeletal malformation and XY sex reversal1–3. During chondrogenesis in the mouse, Sox9 …
skeletal malformation and XY sex reversal1–3. During chondrogenesis in the mouse, Sox9 …
From head to toes: the multiple facets of Sox proteins
M Wegner - Nucleic acids research, 1999 - academic.oup.com
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found
throughout the animal kingdom. They are involved in the regulation of such diverse …
throughout the animal kingdom. They are involved in the regulation of such diverse …
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse
LJ Ng, S Wheatley, GEO Muscat… - Developmental …, 1997 - Elsevier
Two lines of evidence suggest that theSry-related geneSox9is important for chondrogenesis
in mammalian embryos. Sox9mRNA is expressed in chondrogenic condensations in mice …
in mammalian embryos. Sox9mRNA is expressed in chondrogenic condensations in mice …
Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis
Q Zhao, H Eberspaecher, V Lefebvre… - … dynamics: an official …, 1997 - Wiley Online Library
To assess the role of the transcription factor Sox9 in cartilage formation we have compared
the expression pattern of Sox9 and Col2a1 at various stages of mouse embryonic …
the expression pattern of Sox9 and Col2a1 at various stages of mouse embryonic …
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos
E Wright, MR Hargrave, J Christiansen, L Cooper… - Nature …, 1995 - nature.com
Mutations in the human SRY–related gene, SOX9, located on chromosome 17, have
recently been associated with the sex reversal and skeletal dysmorphology syndrome …
recently been associated with the sex reversal and skeletal dysmorphology syndrome …
[HTML][HTML] SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6
SOX9 is a transcription factor that plays a key role in chondrogenesis. Aggrecan is one of the
major structural components in cartilage; however, the molecular mechanism of aggrecan …
major structural components in cartilage; however, the molecular mechanism of aggrecan …