Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …

Throughout evolution, all organisms have harnessed the redox properties of copper (Cu)
and iron (Fe) as a cofactor or structural determinant of proteins that perform critical functions …

Abstract l-Glutathione capped (GSH) ZnSe quantum dots (QDs) have been synthesized as a
fluorescence ions probes for ultrasensitive Cu (II) detection. These QDs surface decoration …

Wilson's disease is an orphan disease due to copper homeostasis dysfunction. Mutations of
the ATP7B gene induces an impaired functioning of a Cu-ATPase, impaired Cu …

The tripeptide glutathione (GSH) is a crucial intracellular reductant and radical scavenger,
but it may also coordinate the soft Cu (I) cation and thereby yield pro-oxidant species. The …

Metal overload plays an important role in several diseases or intoxications, like in Wilson's
disease, a major genetic disorder of copper metabolism in humans. To efficiently and …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder first described in
1906 that is currently estimated to impact∼ 40 million people worldwide. Extensive research …

Natural organic matter (NOM) exerts strong influence on copper speciation and
bioavailability in soils and aquatic systems. In redox-dynamic environments, electron …

Copper oxide nanoparticles (CuO-NP) were studied for their toxicity and mechanism of
action on hepatocytes (HepG2), in relation to Cu homeostasis disruption. Indeed …

Despite the importance of phototrophic biofilms in metal cycling in freshwater systems, metal
isotope fractionation linked to metal adsorption and uptake by biofilm remains very poorly …