Secondary osteoporosis

PR Ebeling, HH Nguyen, J Aleksova… - Endocrine …, 2022 - academic.oup.com
Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Disuse osteoporosis: clinical and mechanistic insights

T Rolvien, M Amling - Calcified tissue international, 2022 - Springer
Disuse osteoporosis describes a state of bone loss due to local skeletal unloading or
systemic immobilization. This review will discuss advances in the field that have shed light …

Effects of neurological disorders on bone health

RR Kelly, SJ Sidles, AC LaRue - Frontiers in psychology, 2020 - frontiersin.org
Neurological diseases, particularly in the context of aging, have serious impacts on quality of
life and can negatively affect bone health. The brain-bone axis is critically important for …

Osteoporosis treatment with anti-sclerostin antibodies—mechanisms of action and clinical application

M Rauner, H Taipaleenmäki, E Tsourdi… - Journal of Clinical …, 2021 - mdpi.com
Osteoporosis is characterized by reduced bone mass and disruption of bone architecture,
resulting in increased risk of fragility fractures and significant long-term disability. Although …

Prevalence of mental health disorders among adults with cerebral palsy: a cross-sectional analysis

DG Whitney, SA Warschausky, S Ng… - Annals of Internal …, 2019 - acpjournals.org
Background: Persons with cerebral palsy (CP) have an increased risk for secondary chronic
conditions during childhood, including mental health disorders. However, little is known …

Age trajectories of musculoskeletal morbidities in adults with cerebral palsy

DG Whitney, EA Hurvitz, MJ Devlin, MS Caird… - Bone, 2018 - Elsevier
Background Individuals with cerebral palsy (CP) are at an increased risk for age-related
morbidities due to functional impairments, maladapted growth, and altered body …

Adults with cerebral palsy have higher prevalence of fracture compared with adults without cerebral palsy independent of osteoporosis and cardiometabolic diseases

DG Whitney, AI Alford, MJ Devlin… - Journal of Bone and …, 2019 - academic.oup.com
Individuals with cerebral palsy (CP) have an increased risk of fracture throughout their
lifespan based on an underdeveloped musculoskeletal system, excess body fat, diminished …

Zoledronate increases bone mineral density in nonambulant children with cerebral palsy: a randomized controlled trial

JB Granild-Jensen, B Møller-Madsen… - The Journal of …, 2023 - academic.oup.com
Context Zoledronate appears to reduce fracture rates in children with cerebral palsy (CP),
but no previous randomized, controlled trial has been performed to compare the effect of …

Multi-organ dysfunction in cerebral palsy

J Allen, Z Zareen, S Doyle, L Whitla, Z Afzal… - Frontiers in …, 2021 - frontiersin.org
Cerebral Palsy (CP) describes a heterogenous group of non-progressive disorders of
posture or movement, causing activity limitation, due to a lesion in the developing brain. CP …

Use of overground supported-stepping devices for non-ambulant children, adolescents, and adults with cerebral palsy: A scoping review

RW Livingstone, GS Paleg - Disabilities, 2023 - mdpi.com
Individuals with cerebral palsy functioning at Gross Motor Function Classification System
(GMFCS) levels IV and V are unable to use hand-held walkers and require supported …