Simple Summary The fusion between sperm and oocyte results in a zygote, which is a single
totipotent cell with the ability to develop into a functional organism. Totipotent cells can give …

Genetic modification of animals via selective breeding is the basis for modern agriculture.
The current breeding paradigm however has limitations, chief among them is the …

In brief The first week of gestation is a period of major pregnancy loss in cattle, this study
reveals that the male plays a key role in regulating embryonic development during this time …

The objective of this study was to evaluate the time of blastulation monitored by time-lapse
technology to predict in vitro viability of bovine blastocysts. This technology can be a …

The role of the pluripotency factor NANOG during the second embryonic lineage
differentiation has been studied extensively in mouse, although species-specific differences …

Bovine embryonic stem cells (ESC) have features associated with the primed pluripotent
state including low expression of one of the core pluripotency transcription factors, NANOG …

Early mammal embryogenesis starts with oocyte fertilization, giving rise to the zygote. The
events that the newly formed zygote surpasses are crucial to the embryo developmental …

Objectives Gene regulation in early embryos has been widely studied for a long time
because lineage segregation gives rise to the formation of a pluripotent cell population …

Objectives Curiosity about the role of OCT4, a core transcription factor that maintains inner
cell mass (ICM) formation during preimplantation embryogenesis and the pluripotent state in …

Besides their canonical roles as energy sources, short‐chain fatty acids act as metabolic
regulators of gene expression through histone posttranslational modifications. Ketone body …