The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …

De novo gene birth is the process by which new genes evolve from DNA sequences that
were ancestrally non-genic. De novo genes represent a subset of novel genes, and may be …

Large-scale genome-structural evolution is common in various organisms. Recent
developments in speciation genomics revealed the importance of inversions, whereas the …

The immense morphological and phenotypic diversity within eukaryotes coincides with large-
scale differences in genic repertoires, including the presence of thousands of new genes in …

De novo gene origination has been recently established as an important mechanism for the
formation of new genes. In organisms with a large genome, intergenic and intronic regions …

Abstract Development can be altered to match phenotypes with the environment, and the
genetic mechanisms that direct such alternative phenotypes are beginning to be elucidated …

Divergence of gene function and expression during development can give rise to phenotypic
differences at the level of cells, tissues, organs, and ultimately whole organisms. To gain …

Environment shapes development through a phenomenon called developmental plasticity.
Deciphering its genetic basis has potential to shed light on the origin of novel traits and …

Long-read sequencing technologies have contributed greatly to comparative genomics
among species and can also be applied to study genomics within a species. In this study, to …

The nematodes C. elegans and P. pacificus populate diverse habitats and display distinct
patterns of behavior. To understand how their nervous systems have diverged, we …