Liquid biopsy enters the clinic—implementation issues and future challenges
M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …
cells in peripheral blood have provided crucial insights into cancer biology and the …
[HTML][HTML] Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer
Background Liquid biopsy (LB) is a rapidly evolving diagnostic tool for precision oncology
that has recently found its way into routine practice as an adjunct to tissue biopsy (TB). The …
that has recently found its way into routine practice as an adjunct to tissue biopsy (TB). The …
Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
MicroRNAs (miRNAs) play essential roles in post-transcriptional gene expression and are
also found freely circulating in bodily fluids such as blood. Dysregulated miRNA signatures …
also found freely circulating in bodily fluids such as blood. Dysregulated miRNA signatures …
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides
attractive opportunities for early diagnosis, assessment of treatment response, and minimally …
attractive opportunities for early diagnosis, assessment of treatment response, and minimally …
Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas
Recurrence of meningiomas is unpredictable by current invasive methods based on
surgically removed specimens. Identification of patients likely to recur using noninvasive …
surgically removed specimens. Identification of patients likely to recur using noninvasive …
Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma
M Lodrini, J Graef, TM Thole-Kliesch… - Clinical Cancer …, 2022 - AACR
Purpose: Treating refractory or relapsed neuroblastoma remains challenging. Monitoring
body fluids for tumor-derived molecular information indicating minimal residual disease …
body fluids for tumor-derived molecular information indicating minimal residual disease …
Detection of clinical progression through plasma ctDNA in metastatic melanoma patients: a comparison to radiological progression
G Marsavela, AC McEvoy, MR Pereira, AL Reid… - British journal of …, 2022 - nature.com
Background The validity of circulating tumour DNA (ctDNA) as an indicator of disease
progression compared to medical imaging in patients with metastatic melanoma requires …
progression compared to medical imaging in patients with metastatic melanoma requires …
Combinatorial power of cfDNA, CTCs and EVs in oncology
Liquid biopsy is a promising technique for clinical management of oncological patients. The
diversity of analytes circulating in the blood useable for liquid biopsy testing is enormous …
diversity of analytes circulating in the blood useable for liquid biopsy testing is enormous …
Consensus recommendations to optimize testing for new targetable alterations in non-small cell lung cancer
DN Ionescu, TL Stockley, S Banerji, C Couture… - Current …, 2022 - mdpi.com
Non-small cell lung cancer (NSCLC) has historically been associated with a poor prognosis
and low 5-year survival, but the use of targeted therapies in NSCLC has improved patient …
and low 5-year survival, but the use of targeted therapies in NSCLC has improved patient …
Liquid biopsy for early diagnosis of non-small cell lung carcinoma: recent research and detection technologies
L Chang, J Li, R Zhang - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Liquid biopsy, an innovative method for early diagnosis of cancer, has changed the
traditional method of diagnosing lung cancer and is considered a feasible auxiliary …
traditional method of diagnosing lung cancer and is considered a feasible auxiliary …