[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

[HTML][HTML] Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells

W Qiu, X Guo, B Li, J Wang, Y Qi, Z Chen, R Zhao… - Molecular Therapy, 2021 - cell.com
Glioma is a heterogeneous cellular environment in which immune cells play critical roles in
tumor progression. Myeloid-derived suppressor cells (MDSCs) contribute to the formation of …

Tumor-derived systems as novel biomedical tools—turning the enemy into an ally

N Desai, P Katare, V Makwana, S Salave… - Biomaterials …, 2023 - spj.science.org
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …

[HTML][HTML] Advanced technologies for molecular diagnosis of cancer: State of pre-clinical tumor-derived exosome liquid biopsies

L Li, L Zhang, KC Montgomery, L Jiang, CJ Lyon… - Materials Today Bio, 2023 - Elsevier
Exosomes are membrane-defined extracellular vesicles (EVs) approximately 40–160​ nm
in diameter that are found in all body fluids including blood, urine, and saliva. They act as …

Focus on the heterogeneity of amyotrophic lateral sclerosis

C Bendotti, V Bonetto, E Pupillo… - … Lateral Sclerosis and …, 2020 - Taylor & Francis
The clinical manifestations of amyotrophic lateral sclerosis (ALS) are variable in terms of age
at disease onset, site of onset, progression of symptoms, motor neuron involvement, and the …

[HTML][HTML] Aptamer-guided extracellular vesicle theranostics in oncology

PHL Tran, D Xiang, TNG Nguyen, TTD Tran, Q Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
In the past decade, the study of exosomes, nanosized vesicles (50-150 nm) released into
the extracellular space via the fusion of multivesicular bodies with the plasma membrane …

[HTML][HTML] Expression of Cellular and Extracellular TERRA, TERC and TERT in Hepatocellular Carcinoma

M Manganelli, I Grossi, J Corsi, VG D'Agostino… - International journal of …, 2022 - mdpi.com
Non-coding RNAs are transcribed from telomeres and the telomeric repeat-containing RNAs
(TERRA) are implicated in telomere homeostasis and in cancer. In this study, we aimed to …