Interplay of heme with macrophages in homeostasis and inflammation
P Pradhan, V Vijayan, F Gueler… - International journal of …, 2020 - mdpi.com
Macrophages are an integral part of the mononuclear phagocyte system that is critical for
maintaining immune homeostasis. They play a key role for initiation and modulation of …
maintaining immune homeostasis. They play a key role for initiation and modulation of …
Immune and metabolic signatures of COVID-19 revealed by transcriptomics data reuse
The current pandemic of coronavirus disease 19 (COVID-19) has affected millions of
individuals and caused thousands of deaths worldwide. The pathophysiology of the disease …
individuals and caused thousands of deaths worldwide. The pathophysiology of the disease …
Proteomics and machine learning approaches reveal a set of prognostic markers for COVID-19 severity with drug repurposing potential
The pestilential pathogen SARS-CoV-2 has led to a seemingly ceaseless pandemic of
COVID-19. The healthcare sector is under a tremendous burden, thus necessitating the …
COVID-19. The healthcare sector is under a tremendous burden, thus necessitating the …
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures
Severely-afflicted COVID-19 patients can exhibit disease manifestations representative of
sepsis, including acute respiratory distress syndrome and multiple organ failure. We …
sepsis, including acute respiratory distress syndrome and multiple organ failure. We …
Noncoding RNAs implication in cardiovascular diseases in the COVID-19 era
Abstract COronaVIrus Disease 19 (COVID-19) is caused by the infection of the Severe Acute
Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2). Although the main clinical …
Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2). Although the main clinical …
Combined transcriptome and proteome leukocyte's profiling reveals up-regulated module of genes/proteins related to low density neutrophils and impaired …
Sepsis is a global health emergency, which is caused by various sources of infection that
lead to changes in gene expression, protein-coding, and metabolism. Advancements in …
lead to changes in gene expression, protein-coding, and metabolism. Advancements in …
Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS
M Eltobgy, F Johns, D Farkas, L Leuenberger… - Frontiers in …, 2024 - frontiersin.org
Introduction The acute respiratory distress syndrome (ARDS) is a common complication of
severe COVID-19 and contributes to patient morbidity and mortality. ARDS is a …
severe COVID-19 and contributes to patient morbidity and mortality. ARDS is a …
Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing
W Zhang, C Yan, X Liu, P Yang, J Wang, Y Chen… - Cancer Gene …, 2022 - nature.com
Megakaryocytes (MK) are mainly derived from bone marrow and are mainly involved in
platelet production. Studies have shown that MK derived from bone marrow may have …
platelet production. Studies have shown that MK derived from bone marrow may have …
Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms
Introduction Severe COVID-19 and non-COVID-19 pulmonary sepsis share
pathophysiological, immunological, and clinical features. To what extent they share …
pathophysiological, immunological, and clinical features. To what extent they share …
[HTML][HTML] Characterization of the plasma proteomic profile of Fabry disease: Potential sex-and clinical phenotype-specific biomarkers
L López-Valverde, ME Vázquez-Mosquera… - Translational …, 2024 - Elsevier
Fabry disease (FD) is a X-linked rare lysosomal storage disorder caused by deficient α-
galactosidase A (α-GalA) activity. Early diagnosis and the prediction of disease course are …
galactosidase A (α-GalA) activity. Early diagnosis and the prediction of disease course are …