[HTML][HTML] Recent developments of synthesis and biological activity of sultone scaffolds in medicinal chemistry

Y Xu, Z Zhang, J Shi, X Liu, W Tang - Arabian Journal of Chemistry, 2021 - Elsevier
Sulfonyl drugs are widely used to treat various types of diseases, in which sultones have
several desirable properties that have led to their increased use, including improving its …

Energy-transfer-powered sultine synthesis

Z Deng, Z Zhu, Z Ru, X Zou, X Ouyang, H Li… - ACS …, 2023 - ACS Publications
Molecules with precise sultine structures are particularly sought after since the function of a
molecule depends on this interesting structure. Despite the positive pivotal significance of …

Synthesis of trifluoromethylated sultones from alkenols using a copper photoredox catalyst

T Rawner, M Knorn, E Lutsker, A Hossain… - The Journal of Organic …, 2016 - ACS Publications
A photo-redox-catalyzed procedure for the one-step formation of sultones from α, ω-alkenols
and trifluoromethylsulfonyl chloride is described. Using [Cu (dap) 2] Cl (1 mol%), a wide …

Electrochemical Synthesis of Sultone Derivatives via Dehydrogenative C–O Bond Formation

K Mitsudo, Y Okumura, K Yohena, Y Kurimoto… - Organic …, 2023 - ACS Publications
Electrochemical dehydrogenative C–O bond formation for the synthesis of sultones was
achieved. In the presence of K2CO3 and H2O, constant current electrolysis of [1, 1 …

Spectroscopic, electrochemical and molecular docking study of the binding interaction of a small molecule 5H-naptho [2, 1-f][1, 2] oxathieaphine 2, 2-dioxide with calf …

A Mukherjee, S Mondal, B Singh - International journal of biological …, 2017 - Elsevier
The interaction of 5H-naptho [2, 1-f][1, 2] oxathieaphine2, 2-dioxide (NOTD) with calf thymus
DNA in Tris-HCl buffer at physiological pH was investigated with the help of various …

One-Pot Sonogashira Coupling–Cyclization toward Regioselective Synthesis of Benzosultams

S Debnath, S Mondal - The Journal of Organic Chemistry, 2015 - ACS Publications
A one-pot method for the Sonogashira coupling and cyclization of 2-
bromobenzenesulfonamides and terminal alkynes is presented. This method allows access …

Recent advances in sultone synthesis (microreview)

A Pustenko, R Žalubovskis - Chemistry of Heterocyclic Compounds, 2017 - Springer
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N-methyl-2-pyrrolidonium chlorosulfonate: an efficient ionic-liquid catalyst and mild sulfonating agent for one-pot synthesis of δ-sultones

K Rad-Moghadam, SARM Hassani… - Journal of Molecular …, 2016 - Elsevier
Addition of chlorosulfonic acid to N-methyl-2-pyrrolidone (NMP) resulted in the formation of a
low-melting solid with the advantages of being reasonably stable for at least 4 months at …

Synthesis of seven-membered fused sultones by reductive Heck cyclization: An investigation for stereochemistry through DFT study

S Mondal, S Debnath, B Das - Tetrahedron, 2015 - Elsevier
An efficient method for the synthesis of seven-membered fused sultones via Pd (0) catalyzed
intramolecular reductive Heck cyclization is reported. The method offers the regio-and …

Synthesis of uracil-, coumarin-and quinolone-fused benzosultams and benzosultones

S Mondal, S Debnath, S Pal, A Das - Synthesis, 2015 - thieme-connect.com
An efficient method for the regioselective synthesis of uracil-, coumarin-and quinolone-fused
benzosultams and benzosultones is reported. The method offers a synthetic route to highly …