DNA methylation-based predictors of health: applications and statistical considerations
DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …
development, because, unlike static genetic risk estimates, DNA methylation varies …
[HTML][HTML] Systematic review and meta-analysis to examine intrapartum interventions, and maternal and neonatal outcomes following immersion in water during labour …
E Burns, C Feeley, PJ Hall, J Vanderlaan - BMJ open, 2022 - bmjopen.bmj.com
Objectives Water immersion during labour using a birth pool to achieve relaxation and pain
relief during the first and possibly part of the second stage of labour is an increasingly …
relief during the first and possibly part of the second stage of labour is an increasingly …
[HTML][HTML] FASDetect as a machine learning-based screening app for FASD in youth with ADHD
L Ehrig, AC Wagner, H Wolter, CU Correll… - npj Digital …, 2023 - nature.com
Fetal alcohol-spectrum disorder (FASD) is underdiagnosed and often misdiagnosed as
attention-deficit/hyperactivity disorder (ADHD). Here, we develop a screening tool for FASD …
attention-deficit/hyperactivity disorder (ADHD). Here, we develop a screening tool for FASD …
[HTML][HTML] A novel machine learning model to predict respiratory failure and invasive mechanical ventilation in critically ill patients suffering from COVID-19
I Bendavid, L Statlender, L Shvartser, S Teppler… - Scientific Reports, 2022 - nature.com
In hypoxemic patients at risk for developing respiratory failure, the decision to initiate
invasive mechanical ventilation (IMV) may be extremely difficult, even more so among …
invasive mechanical ventilation (IMV) may be extremely difficult, even more so among …
[HTML][HTML] Differences in estimates for 10-year risk of cardiovascular disease in Black versus White individuals with identical risk factor profiles using pooled cohort …
RS Vasan, E van den Heuvel - The Lancet Digital Health, 2022 - thelancet.com
Background Sex-specific and race-specific pooled cohort equations (PCEs) are
recommended for estimating the 10-year risk of cardiovascular disease, with an absolute …
recommended for estimating the 10-year risk of cardiovascular disease, with an absolute …
Dealing with small samples in football research
A Hecksteden, R Kellner, L Donath - Science and medicine in …, 2022 - Taylor & Francis
In football research,'small'trials with low statistical power are common. On the elite level, the
inherently low number of participants obviously conflicts with the relevance of even tiny …
inherently low number of participants obviously conflicts with the relevance of even tiny …
[HTML][HTML] A scoping review of causal methods enabling predictions under hypothetical interventions
Background The methods with which prediction models are usually developed mean that
neither the parameters nor the predictions should be interpreted causally. For many …
neither the parameters nor the predictions should be interpreted causally. For many …
[HTML][HTML] A causal framework for making individualized treatment decisions in oncology
Simple Summary Physicians routinely make individualized treatment decisions by
accounting for the joint effects of patient prognostic covariates and treatments on clinical …
accounting for the joint effects of patient prognostic covariates and treatments on clinical …
[HTML][HTML] English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections
Abstract Background The English Bulldog has risen sharply in popularity over the past
decade but its distinctive and extreme conformation is linked to several serious health …
decade but its distinctive and extreme conformation is linked to several serious health …
Predictive models for clinical decision making: Deep dives in practical machine learning
S Eloranta, M Boman - Journal of Internal Medicine, 2022 - Wiley Online Library
The deployment of machine learning for tasks relevant to complementing standard of care
and advancing tools for precision health has gained much attention in the clinical …
and advancing tools for precision health has gained much attention in the clinical …