A critical review on the dissemination of PH and stimuli-responsive polymeric nanoparticular systems to improve drug delivery in cancer therapy

S Bhattacharya, BG Prajapati, S Singh - Critical Reviews in Oncology …, 2023 - Elsevier
Stimuli-responsive nanocarriers have the potential to revolutionize cancer treatment by
allowing precise delivery of drugs to the site of disease. The use of polymeric nanocarriers …

Stimuli‐responsive silk fibroin for on‐demand drug delivery

X Lin, L Cai, X Cao, Y Zhao - Smart Medicine, 2023 - Wiley Online Library
Stimuli‐responsive “smart” hydrogel biomaterials have attracted great attention in the
biomedical field, especially in designing novel on‐demand drug delivery systems. As a …

Exploring the application of micellar drug delivery systems in cancer nanomedicine

Q Wang, K Atluri, AK Tiwari, RJ Babu - Pharmaceuticals, 2023 - mdpi.com
Various formulations of polymeric micelles, tiny spherical structures made of polymeric
materials, are currently being investigated in preclinical and clinical settings for their …

Prodrug approaches for the development of a long-acting drug delivery systems

ST Chien, IT Suydam, KA Woodrow - Advanced Drug Delivery Reviews, 2023 - Elsevier
Long-acting formulations are designed to reduce dosing frequency and simplify dosing
schedules by providing an extended duration of action. One approach to obtain long-acting …

Secondary Structures in Synthetic Poly (Amino Acids): Homo‐and Copolymers of Poly (Aib), Poly (Glu), and Poly (Asp)

M Rohmer, J Freudenberg… - Macromolecular …, 2023 - Wiley Online Library
The secondary structure of poly (amino acids) is an excellent tool for controlling and
understanding the functionality and properties of proteins. In this perspective article the …

Synchronized delivery of dual-drugs for potentiating combination chemotherapy based on smart triple-responsive polymeric micelles

Y Liu, P Guo, X Dong, Y Xu, D Li, H Zheng, J Liao - Biomaterials Advances, 2023 - Elsevier
Here, we combined reversible addition-fragmentation chain transfer (RAFT) polymerization
and amide coupling reaction to develop a novel drug-polymer conjugate using poly (AMA-co …

Effect of Hydrophobic Chain Length in Amphiphilic Chitosan Conjugates on Intracellular Drug Delivery and Smart Drug Release of Redox-Responsive Micelle

Y Yuan, W Tan, Y Mi, L Wang, Z Qi, Z Guo - Marine Drugs, 2023 - mdpi.com
Three redox-sensitive nanocarriers were rationally designed based on amphiphilic low
molecular weight chitosan-cystamine-octylamine/dodecylamin/cetylamine (LC-Cys-OA, LC …

Micelle-based nanoparticles with stimuli-responsive properties for drug delivery

AH Maboudi, MH Lotfipour, M Rasouli… - Nanotechnology …, 2024 - degruyter.com
Cancer treatment often causes adverse effects and toxicity, as chemotherapy drugs affect
both cancerous and healthy cells. Scientists seek to target tumor cells specifically and …

Doxorubicin-loaded Polymeric Biotin-PEG-SeSe-PBLA Micelles with surface Binding of Biotin-Mediated Cancer Cell Targeting and Redox-Responsive Drug release …

HT Gebrie, D Thankachan, HC Tsai, JY Lai… - Colloids and Surfaces B …, 2024 - Elsevier
Biotin receptors are overexpressed in various cancer cell types, essential in tumor
development, metabolism, and metastasis. Chemotherapeutic agents may be more effective …

Polymeric core-crosslinked particles prepared via a nanoemulsion-mediated process: from particle design and structural characterization to in vivo behavior in …

S Fujii - Polymer Journal, 2023 - nature.com
Various polymeric nanoparticles have been used as drug carriers in drug delivery systems
(DDSs). Most of them were constructed from dynamic self-assembly systems formed via …