Extremophilic microorganisms have established a diversity of molecular strategies in order
to survive in extreme conditions. Biocatalysts isolated by these organisms are termed …

The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

Pre-treatments for waste activated sludge (WAS) are, in most cases, an attempt to increase
the biodegradation and/or improve hydrolysis rate of WAS after anaerobic digestion. This …

Extremophiles, especially those in Archaea, have a myriad of adaptations that keep their
cellular proteins stable and active under the extreme conditions in which they live. Rather …

Pollution, accidents, and misinformation have earned the pharmaceutical and chemical
industry a poor public reputation, despite their undisputable importance to society …

A number of machine learning (ML)-based algorithms have been proposed for predicting
mutation-induced stability changes in proteins. In this critical review, we used hypothetical …

Grape pomace (GP) is a low-value by-product that contains a significant amount of high
value-added products. The huge amount of non-edible residues of GP wastes (seeds, skins …

Thermophilic microorganisms are attractive candidates for conversion of lignocellulose to
biofuels because they produce robust, effective, carbohydrate-degrading enzymes and …

Protein engineering is a powerful strategy for enhancing the properties of enzymes for
industrial applications. However, thermostabilizing an enzyme via this strategy while …

In biosensors and biofuel cells, it is often desirable to accelerate the electron transfer rate
between the enzyme and electrode surface to improve the performance of the devices …