Management of Mechanical Prosthetic Heart Valve Thrombosis: JACC Review Topic of the Week

CE Soria Jiménez, AI Papolos, BB Kenigsberg… - Journal of the American …, 2023 - jacc.org
Mechanical prosthetic heart valves, though more durable than bioprostheses, are more
thrombogenic and require lifelong anticoagulation. Mechanical valve dysfunction can be …

Mechanical valve thrombosis: Current management and differences between guidelines

A Serban, D Gavan, D Pepine, A Dadarlat… - Trends in …, 2023 - Elsevier
All foreign bodies inserted in the circulatory system are thrombogenic and require temporary
or lifelong antithrombotic therapies to prevent thrombosis. The adequate level of …

Acute heart failure and valvular heart disease: A scientific statement of the Heart Failure Association, the Association for Acute CardioVascular Care and the European …

O Chioncel, M Adamo, M Nikolaou… - European Journal of …, 2023 - Wiley Online Library
Acute heart failure (AHF) represents a broad spectrum of disease states, resulting from the
interaction between an acute precipitant and a patient's underlying cardiac substrate and …

Fibrinolytic agents in thromboembolic diseases: historical perspectives and approved indications

S Rashedi, CM Greason, P Sadeghipour… - … in Thrombosis and …, 2024 - thieme-connect.com
Fibrinolytic agents catalyze the conversion of the inactive proenzyme plasminogen into the
active protease plasmin, degrading fibrin within the thrombus and recanalizing occluded …

Mechanical Prosthetic Valve Thrombosis: A Literature Review of Treatment Strategies

P Ebrahimi, B Sattartabar, H Taheri, P Soltani… - Current Problems in …, 2024 - Elsevier
Mechanical prosthetic valve thrombosis (MPVT) is a common complication of valvular
implantations. This study compared the efficacy and safety of different treatments for MPVT …

Combination anticoagulation strategy in pregnancy with mechanical valves: The KYBELE study

M Özkan, A Güner, S Gündüz, G Yıldız, Aİ Yıldırım… - American Heart …, 2024 - Elsevier
Background Optimal first-trimester anticoagulation is still challenging in pregnant women
with mechanical heart valves (MHVs) requiring high-dose warfarin. This multicenter …

Monocyte to HDL ratio may predict thrombosis in patients with mechanical mitral and aortic valve prosthesis

MO Gürsoy, C Yılmaz, E Bayam, A Güner… - Journal of Artificial …, 2024 - Springer
Increased inflammatory biomarkers have been reported in prosthetic heart valve thrombosis
(PHVT). Monocyte to HDL ratio (MHR) and albumin to CRP levels (CAR) are two biomarkers …

Clinical Outcomes of Percutaneous Transcatheter Release of Stuck Mechanical Mitral Valve With Cerebral Embolic Protection

V Nandhakumar, L Kalidoss, J Ezhilan… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Surgery or fibrinolysis is the currently available evidence-based treatment
for obstructive mechanical valve thrombus. We reported the feasibility and short-term …

Thromboaspiration of a left-sided bioprosthetic valve thrombosis by a mini-access: the Lausanne novel procedure

Z Gunga, V Rubimbura, D Oberson… - Frontiers in …, 2024 - frontiersin.org
Left-sided bioprosthesis valve thrombosis (LSBVT) is a challenging complication
necessitating invasive interventions. In this study, we introduce a novel, minimally invasive …

Management of prosthetic valve thrombosis with unfractionated heparin

S Kalkan, MO Gürsoy, A Güner, M Kalçık… - International Journal of …, 2024 - Elsevier
Background Prosthetic valve thrombosis (PVT) is a severe and life-threatening complication.
Surgery and thrombolytic therapy (TT) carry a high risk, and in several circumstances …