Triglyceride-rich lipoproteins deliver fatty acids to tissues for oxidation and for storage.
Release of fatty acids from circulating lipoprotein triglycerides is carried out by lipoprotein …

M any processes have been implicated in early atherogenesis. These include endothelial
denudation, injury, or activation, including shear stress-related events; local adherence of …

Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes
triglyceride in chylomicrons, during the past half decade there has been a reinterest in the …

The plasma clearance of intestinally derived remnant lipoproteins by the liver is a process
that likely involves three steps. Our model suggests that the initial rapid clearance by the …

Increased levels of apolipoprotein B (apoB)-containing lipoproteins, such as low density
lipoproteins (LDL) and chylomicron remnants, are associated with the development of …

All organisms use fatty acids (FAs) for energy substrates and as precursors for membrane
and signaling lipids. The most efficient way to transport and store FAs is in the form of …

Lipoprotein lipase (LPL) plays a major role in the lipid homeostasis mainly by mediating the
intravascular lipolysis of triglyceride rich lipoproteins. Impaired LPL activity leads to the …

Heparin and HS are glycosaminoglycans (GAGS), and are synthesized as proteoglycans in
which the GAG chains are covalently bound to serine residues of core proteins. GAGS are …

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolism and responsible for catalyzing
lipolysis of triglycerides in lipoproteins. LPL is produced mainly in adipose tissue, skeletal …

Heparan sulfate (HS) can bind a large variety of biological effectors, including extracellular
matrix components, growth factors, chemokines, degradative enzymes, and protease …