Adipose tissue secretes adipokines that mediate insulin resistance, a characteristic feature
of obesity and type 2 diabetes. By differential proteome analysis of cellular models of insulin …

Simple Summary Urogenital cancers (prostate, bladder, kidney) have significant global
health impacts. Proteomic biomarkers are emerging tools that aim to improve early detection …

Worldwide, over 273,000 people are diagnosed with renal cancer each year. Approximately
one third of patients present with locally advanced or metastatic disease and although …

Abstract Clear cell Renal Cell Carcinoma (ccRCC) causes over 13,000 deaths each year,
and about 20,000 new cases/year in Europe. In most cases, the causes are unknown and …

Background: Proteomics-based approaches for biomarker discovery are promising
strategies used in cancer research. We present state-of-art label-free quantitative proteomics …

The knockout (KO) of the cystine transporter xCT causes ferroptosis, a type of iron-
dependent necrotic cell death, in mouse embryonic fibroblasts, but this does not occur in …

Renal cell carcinoma (RCC) is frequently diagnosed incidentally as an early‐stage small
renal mass (SRM; pT1a,≤ 4 cm). Overtreatment of patients with benign or clinically indolent …

To discover candidate biomarkers for diagnosis and detection of human laryngeal
carcinoma and explore possible mechanisms of this cancer carcinogenesis, two …

The analysis of serum endogenous peptides holds promise for disease study and drug
discovery, whereas it is relatively unexplored given its challenges in analysis reproducibility …

Renal cell carcinoma (RCC) biomarkers are necessary for diagnosis and prognosis. They
serve to monitor therapy response and follow-up, as drug targets, and therapy predictors in …