The potential of the mevalonate pathway for enhanced isoprenoid production
The cytosol-localised mevalonic acid (MVA) pathway delivers the basic isoprene unit
isopentenyl diphosphate (IPP). In higher plants, this central metabolic intermediate is also …
isopentenyl diphosphate (IPP). In higher plants, this central metabolic intermediate is also …
Glandular trichomes: what comes after expressed sequence tags?
A Tissier - The Plant Journal, 2012 - Wiley Online Library
Glandular trichomes cover the surface of many plant species. They exhibit tremendous
diversity, be it in their shape or the compounds they secrete. This diversity is expressed …
diversity, be it in their shape or the compounds they secrete. This diversity is expressed …
Metabolic engineering of microorganisms for the synthesis of plant natural products
J Marienhagen, M Bott - Journal of biotechnology, 2013 - Elsevier
Of more than 200,000 plant natural products known to date, many demonstrate important
pharmacological activities or are of biotechnological significance. However, isolation from …
pharmacological activities or are of biotechnological significance. However, isolation from …
Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities
Terpenoids (aka isoprenoids) represent the most diverse class of natural products found in
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
plants, with tens of thousands of reported structures. Plant‐derived terpenoids have a …
A review of biotechnological artemisinin production in plants
NKBK Ikram, HT Simonsen - Frontiers in Plant Science, 2017 - frontiersin.org
Malaria is still an eminent threat to major parts of the world population mainly in sub-
Saharan Africa. Researchers around the world continuously seek novel solutions to either …
Saharan Africa. Researchers around the world continuously seek novel solutions to either …
Functional analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase encoding genes in triterpene saponin-producing ginseng
YJ Kim, OR Lee, JY Oh, MG Jang, DC Yang - Plant physiology, 2014 - academic.oup.com
Ginsenosides are glycosylated triterpenes that are considered to be important
pharmaceutically active components of the ginseng (Panax ginseng 'Meyer') plant, which is …
pharmaceutically active components of the ginseng (Panax ginseng 'Meyer') plant, which is …
Artemisinins in combating viral infections like SARS-CoV-2, inflammation and cancers and options to meet increased global demand
K Farmanpour-Kalalagh… - Frontiers in Plant …, 2022 - frontiersin.org
Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …
Variation in terpenoids in leaves of Artemisia annua grown under different LED spectra resulting in diverse antimalarial activities against Plasmodium falciparum
D Sankhuan, G Niramolyanun, N Kangwanrangsan… - BMC Plant …, 2022 - Springer
Background Productivities of bioactive compounds in high-value herbs and medicinal plants
are often compromised by uncontrollable environmental parameters. Recent advances in …
are often compromised by uncontrollable environmental parameters. Recent advances in …
From plant to yeast—Advances in biosynthesis of artemisinin
L Zhao, Y Zhu, H Jia, Y Han, X Zheng, M Wang… - Molecules, 2022 - mdpi.com
Malaria is a life-threatening disease. Artemisinin-based combination therapy (ACT) is the
preferred choice for malaria treatment recommended by the World Health Organization. At …
preferred choice for malaria treatment recommended by the World Health Organization. At …
Plants as sources of natural and recombinant antimalaria agents
Malaria is one of the severe infectious diseases that has victimized about half a civilization
billion people each year worldwide. The application of long-lasting insecticides is the main …
billion people each year worldwide. The application of long-lasting insecticides is the main …