Overview on chikungunya virus infection: from epidemiology to state-of-the-art experimental models

LEC Constant, BF Rajsfus, PH Carneiro… - Frontiers in …, 2021 - frontiersin.org
Chikungunya virus (CHIKV) is currently one of the most relevant arboviruses to public
health. It is a member of the Togaviridae family and alphavirus genus and causes an …

Experimental models for the study of central nervous system infection by SARS-CoV-2

I Sanclemente-Alaman, L Moreno-Jiménez… - Frontiers in …, 2020 - frontiersin.org
Introduction The response to the SARS-CoV-2 coronavirus epidemic requires increased
research efforts to expand our knowledge of the disease. Questions related to infection rates …

Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses

G Garcia, JI Irudayam, AV Jeyachandran, S Dubey… - Cell Reports …, 2023 - cell.com
RNA viruses continue to remain a threat for potential pandemics due to their rapid evolution.
Potentiating host antiviral pathways to prevent or limit viral infections is a promising strategy …

Evaluation of the 50% infectious dose of human norovirus Cin-2 in gnotobiotic pigs: A comparison of classical and contemporary methods for endpoint estimation

AK Ramesh, V Parreño, PJ Schmidt, S Lei, W Zhong… - Viruses, 2020 - mdpi.com
Human noroviruses (HuNoVs) are the leading causative agents of epidemic and sporadic
acute gastroenteritis that affect people of all ages worldwide. However, very few dose …

CHIKV strains Brazil (wt) and Ross (lab-adapted) differ with regard to cell host range and antiviral sensitivity and show CPE in human glioblastoma cell lines U138 and …

FIL Hucke, M Bestehorn-Willmann, M Bassetto… - Virus Genes, 2022 - Springer
Abstract Chikungunya virus (CHIKV), a (re) emerging arbovirus, is the causative agent of
chikungunya fever. To date, no approved vaccine or specific antiviral therapy are available …

First report of the detection of DENV1 in human blood plasma with near-infrared spectroscopy

B Goh, P Visendi, AR Lord, S Ciocchetta, W Liu… - Viruses, 2022 - mdpi.com
Dengue virus (DENV) is the world's most common arboviral infection, with an estimated 3.9
million people at risk of the infection, 100 million symptomatic cases and 10,000 deaths per …

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

MS Hakim, AT Aman - Viruses, 2022 - mdpi.com
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by
the sudden onset of symptoms, including fever, rash, myalgia, and headache. In some …

Chikungunya Virus, Metabolism, and Circadian Rhythmicity Interplay in Phagocytic Cells

L Alvarez-García, FJ Sánchez-García… - Metabolites, 2023 - mdpi.com
Chikungunya virus (CHIKV) is transmitted to humans by mosquitoes of the genus Aedes,
causing the chikungunya fever disease, associated with inflammation and severe articular …

Antiviral and Virucidal Activities of Uncaria tomentosa (Cat's Claw) against the Chikungunya Virus

RC de Lima, LMM Valente, D Familiar Macedo… - Viruses, 2024 - mdpi.com
Uncaria tomentosa (UT) is a medicinal plant popularly known as cat's claw belonging to the
Rubiaceae family that has been reported to display antiviral and anti-inflammatory activities …

Tropism and immune response of chikungunya and zika viruses: An overview

S Ravindran, A Lahon - Cytokine, 2023 - Elsevier
Zika virus (ZIKV) and chikungunya virus (CHIKV) are two medically important vector-borne
viruses responsible for causing significant disease burden in humans, including …