Human papillomaviruses: diversity, infection and host interactions

AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …

Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications

CH Chung, ML Gillison - Clinical cancer research, 2009 - AACR
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with
an annual incidence of approximately 400,000 worldwide. Although the principal risk factors …

Oral mucosal organoids as a potential platform for personalized cancer therapy

E Driehuis, S Kolders, S Spelier, K Lõhmussaar… - Cancer discovery, 2019 - AACR
Previous studies have described that tumor organoids can capture the diversity of defined
human carcinoma types. Here, we describe conditions for long-term culture of human …

Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan

JN Roberts, CB Buck, CD Thompson, R Kines… - Nature medicine, 2007 - nature.com
Genital human papillomavirus (HPV) infection is the most common sexually transmitted
infection, and virtually all cases of cervical cancer are attributable to infection by a subset of …

Establishment of human papillomavirus infection requires cell cycle progression

D Pyeon, SM Pearce, SM Lank, P Ahlquist… - PLoS …, 2009 - journals.plos.org
Human papillomaviruses (HPVs) are DNA viruses associated with major human cancers. As
such there is a strong interest in developing new means, such as vaccines and microbicides …

APOBEC3A functions as a restriction factor of human papillomavirus

CJ Warren, T Xu, K Guo, LM Griffin, JA Westrich… - Journal of …, 2015 - Am Soc Microbiol
Human papillomaviruses (HPVs) are small DNA viruses causally associated with benign
warts and multiple cancers, including cervical and head-and-neck cancers. While the vast …

Mechanisms of cell entry by human papillomaviruses: an overview

CAJ Horvath, GAV Boulet, VM Renoux, PO Delvenne… - Virology journal, 2010 - Springer
As the primary etiological agents of cervical cancer, human papillomaviruses (HPVs) must
deliver their genetic material into the nucleus of the target cell. The viral capsid has evolved …

The evolving field of human papillomavirus receptor research: a review of binding and entry

AB Raff, AW Woodham, LM Raff, JG Skeate… - Journal of …, 2013 - Am Soc Microbiol
Human papillomaviruses (HPVs) infect epithelia and can lead to the development of lesions,
some of which have malignant potential. HPV type 16 (HPV16) is the most oncogenic …

The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

UA Hasan, C Zannetti, P Parroche… - Journal of Experimental …, 2013 - rupress.org
Human papillomavirus type 16 (HPV16) and other oncogenic viruses have been reported to
deregulate immunity by suppressing the function of the double-stranded DNA innate sensor …

Replication and assembly of human papillomaviruses

MJ Conway, C Meyers - Journal of dental research, 2009 - journals.sagepub.com
Human papillomaviruses (HPVs) are small dsDNA tumor viruses, which are the etiologic
agents of most cervical cancers and are associated with a growing percentage of …