Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

The controversial role of human gut lachnospiraceae

M Vacca, G Celano, FM Calabrese, P Portincasa… - Microorganisms, 2020 - mdpi.com
The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

[HTML][HTML] Dietary lipids, gut microbiota and lipid metabolism

M Schoeler, R Caesar - Reviews in Endocrine and Metabolic Disorders, 2019 - Springer
The gut microbiota is a central regulator of host metabolism. The composition and function of
the gut microbiota is dynamic and affected by diet properties such as the amount and …

Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo… - Nature, 2020 - nature.com
Consumption of fructose has risen markedly in recent decades owing to the use of sucrose
and high-fructose corn syrup in beverages and processed foods, and this has contributed to …

Postbiotics and their potential applications in early life nutrition and beyond

CAM Wegh, SY Geerlings, J Knol, G Roeselers… - International journal of …, 2019 - mdpi.com
Postbiotics are functional bioactive compounds, generated in a matrix during fermentation,
which may be used to promote health. The term postbiotics can be regarded as an umbrella …

[HTML][HTML] Understanding the role of the gut microbiome and microbial metabolites in non-alcoholic fatty liver disease: current evidence and perspectives

N Vallianou, GS Christodoulatos, I Karampela… - Biomolecules, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. NAFLD begins as a relatively benign hepatic steatosis which can evolve to non …

[HTML][HTML] Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health

ES Chambers, T Preston, G Frost, DJ Morrison - Current nutrition reports, 2018 - Springer
Abstract Purpose of this Review This review assesses the latest evidence linking short-chain
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …

Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …