[HTML][HTML] Insights on production mechanism and industrial applications of renewable propylene glycol

JA Okolie - Iscience, 2022 - cell.com
Propylene glycol is a ubiquitous sustainable chemical that have several industrial
applications. It can be used as a non-toxic antifreeze, moisturizers, and in cosmetics …

[HTML][HTML] Solubility Characteristics of Acetaminophen and Phenacetin in Binary Mixtures of Aqueous Organic Solvents: Experimental and Deep Machine Learning …

P Cysewski, T Jeliński, M Przybyłek, W Nowak… - Pharmaceutics, 2022 - mdpi.com
The solubility of active pharmaceutical ingredients is a mandatory physicochemical
characteristic in pharmaceutical practice. However, the number of potential solvents and …

Automated and material-sparing workflow for the measurement of crystal nucleation and growth kinetics

RJ Arruda, PAJ Cally, A Wylie, N Shah… - Crystal Growth & …, 2023 - ACS Publications
The development of digital twins for model-based crystallization process development is
often limited by the associated material-intensive and time-intensive experimental …

Investigation on the Hansen solubility parameter, solvent effect and thermodynamic analysis of indapamide dissolution and molecular dynamics simulation

Y Cong, C Du, M Wang, Z Jiang, K Xing, Y Bian… - Journal of Molecular …, 2021 - Elsevier
In this work, the dissolution behavior of indapamide (IDP) in different solvents was
researched. Solubility of IDP in methanol, ethanol, acetonitrile, 1-propanol, ethyl acetate, 2 …

Investigation on Hansen solubility parameter, solvent effect and thermodynamic properties of 3-methylflavone-8-carboxylic acid dissolved in different solvents

Z Wang, Y Peng, X Cheng, J Yang, B Zhou, L Mi… - Journal of Molecular …, 2022 - Elsevier
In this work, the dissolution behavior of a novel pharmacological factor, 3-methylflavone-8-
carboxylic acid (MFCA) in different solvents was studied. Firstly, the solubility of MFCA in ten …

Acetaminophen solubility in aqueous solutions of betaine-propylene glycol natural deep eutectic solvent at different temperatures

M Barzegar-Jalali, P Jafari, A Jouyban - Journal of Molecular Liquids, 2022 - Elsevier
This work reports the aqueous solubility of acetaminophen (ACP), a most traditionally used
analgesics and antipyretic drug, in betaine/propylene glycol deep eutectic solvent (Bet/PG …

Research on solubility modelling of actarit in different solvents: Solvent effect, Hansen solubility parameter, molecular interactions and solution thermodynamics

Y Cong, C Du, K Xing, Y Bian, X Li, M Wang - Journal of Molecular Liquids, 2022 - Elsevier
The solubility as an important property should be known in terms of design and development
of dosage form, screening of crystal forms along with purification and production for …

Solid-liquid phase equilibrium of nimesulide (Form I) in twelve mono-solvents: Solubility determination, molecular dynamic simulation, solvent effect, model correlation …

J Sha, D Fan, J Zhang, Z Cao, Y Wan, R Sun… - Journal of Molecular …, 2021 - Elsevier
The equilibrium solubility of nimesulide (NIMS) in twelve single solvents was accurately
measured by a laser monitoring method. It was indicated that the positive impact of …

Study of mesalazine solubility in ternary mixtures of ethanol, propylene glycol, and water at various temperatures

E Rahimpour, F Martinez, S Hemmati… - Journal of …, 2022 - Elsevier
Mesalazine is a low-permeable and low-soluble drug, which makes it a class IV drug in the
Biopharmaceutics Classification System. Hence, its solubilization can be helpful for various …

[HTML][HTML] Equilibrium solubility of acetaminophen in ternary mixtures as a tool for design of concentrated parenteral medications

A Romdhani, F Martínez, DA Chiappetta… - Journal of Solution …, 2024 - Springer
The main purpose of this research was to evaluate the mass/volume percentage (% m/v)
solubility of acetaminophen (ACP) in {ethanol (EtOH)(1)+ propylene glycol (PG)(2)+ water …