[HTML][HTML] MLL-rearranged leukemias—an update on science and clinical approaches
AC Winters, KM Bernt - Frontiers in pediatrics, 2017 - frontiersin.org
The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific
MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of …
MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of …
Recent progress in the treatment of cancer in children
E Butler, K Ludwig, HL Pacenta… - CA: a cancer journal …, 2021 - Wiley Online Library
Although significant improvements have been made in the outcomes of children with cancer,
the pace of improvement has slowed in recent years as the limits of therapy intensification …
the pace of improvement has slowed in recent years as the limits of therapy intensification …
[HTML][HTML] Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012
M Rasche, M Zimmermann, L Borschel, JP Bourquin… - Leukemia, 2018 - nature.com
Overall survival (OS) of pediatric patients with acute myeloid leukemia (AML) increased in
recent decades. However, it remained unknown whether advances in first-line treatment …
recent decades. However, it remained unknown whether advances in first-line treatment …
Pediatric cancer mortality and survival in the United States, 2001‐2016
Background Although pediatric cancer mortality and survival have improved in the United
States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and …
States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and …
[HTML][HTML] Pediatric acute myeloid leukemia—past, present, and future
D Reinhardt, E Antoniou, K Waack - Journal of clinical medicine, 2022 - mdpi.com
JCM | Free Full-Text | Pediatric Acute Myeloid Leukemia—Past, Present, and Future Next
Article in Journal Sexual Habits and Sexual Dysfunctions in a Sample of Patients with Psychotic …
Article in Journal Sexual Habits and Sexual Dysfunctions in a Sample of Patients with Psychotic …
[HTML][HTML] Cytogenetics of pediatric acute myeloid leukemia: a review of the current knowledge
J Quessada, W Cuccuini, P Saultier, M Loosveld… - Genes, 2021 - mdpi.com
Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …
[HTML][HTML] Pediatric AML: from biology to clinical management
JDE De Rooij, CM Zwaan… - Journal of clinical …, 2015 - mdpi.com
Pediatric acute myeloid leukemia (AML) represents 15%–20% of all pediatric acute
leukemias. Survival rates have increased over the past few decades to~ 70%, due to …
leukemias. Survival rates have increased over the past few decades to~ 70%, due to …
[HTML][HTML] Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children's Oncology …
New therapeutic strategies are needed for pediatric acute myeloid leukemia (AML) to reduce
disease recurrence and treatment-related morbidity. The Children's Oncology Group Phase …
disease recurrence and treatment-related morbidity. The Children's Oncology Group Phase …
How I treat pediatric acute myeloid leukemia
JE Rubnitz, GJL Kaspers - Blood, The Journal of the American …, 2021 - ashpublications.org
Abstract Treatment outcomes for pediatric patients with acute myeloid leukemia (AML) have
continued to lag behind outcomes reported for children with acute lymphoblastic leukemia …
continued to lag behind outcomes reported for children with acute lymphoblastic leukemia …
Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy
CW Elgarten, R Aplenc - Current Opinion in Pediatrics, 2020 - journals.lww.com
Further incorporation of genomic and molecular data in pediatric AML will allow for
additional refinements in risk stratification to enable the tailoring of treatment intensity. These …
additional refinements in risk stratification to enable the tailoring of treatment intensity. These …