Seeing the complete picture: proteins in top-down mass spectrometry
Top-down protein mass spectrometry can provide unique insights into protein sequence and
structure, including precise proteoform identification and study of protein–ligand and protein …
structure, including precise proteoform identification and study of protein–ligand and protein …
Chromatographic separation of peptides and proteins for characterization of proteomes
Y Liang, L Zhang, Y Zhang - Chemical Communications, 2023 - pubs.rsc.org
Characterization of proteomes aims to comprehensively characterize proteins in cells or
tissues via two main strategies:(1) bottom-up strategy based on the separation and …
tissues via two main strategies:(1) bottom-up strategy based on the separation and …
Expanding Orbitrap Collision Cross-Section Measurements to Native Protein Applications Through Kinetic Energy and Signal Decay Analysis
The measurement of collision cross sections (CCS, σ) offers supplemental information about
sizes and conformations of ions beyond mass analysis alone. We have previously shown …
sizes and conformations of ions beyond mass analysis alone. We have previously shown …
Investigating lipid transporter protein and lipid interactions using variable temperature electrospray ionization, ultraviolet photodissociation mass spectrometry, and …
Gram-negative bacteria develop and exhibit resistance to antibiotics, owing to their highly
asymmetric outer membrane maintained by a group of six proteins comprising the Mla …
asymmetric outer membrane maintained by a group of six proteins comprising the Mla …
[HTML][HTML] Establishing 20S proteasome genetic, translational and post-translational status from precious biological and patient samples with top-down MS
AS Dafun, D Živković, SA Leon-Icaza, S Möller… - Cells, 2023 - mdpi.com
The mammalian 20S catalytic core of the proteasome is made of 14 different subunits (α1-7
and β1-7) but exists as different subtypes depending on the cell type. In immune cells, for …
and β1-7) but exists as different subtypes depending on the cell type. In immune cells, for …
Native mass spectrometry reveals binding interactions of SARS-CoV-2 PLpro with inhibitors and ISG15
Here we used native mass spectrometry (native MS) to probe a SARS-CoV protease, PLpro,
which plays critical roles in coronavirus disease by affecting viral protein production and …
which plays critical roles in coronavirus disease by affecting viral protein production and …
Hydrophilic interaction chromatography coupled to ultraviolet photodissociation affords identification, localization, and relative quantitation of glycans on intact …
Protein glycosylation is implicated in a wide array of diseases, yet glycoprotein analysis
remains elusive owing to the extreme heterogeneity of glycans including microheterogeneity …
remains elusive owing to the extreme heterogeneity of glycans including microheterogeneity …
[PDF][PDF] Establishing 20S Proteasome Genetic, Translational and Post-Translational Status from Precious Biological and Patient Samples with Top-Down MS. Cells …
AS Dafun, D Živkovic, SA Leon-Icaza, S Möller… - 2023 - academia.edu
The mammalian 20S catalytic core of the proteasome is made of 14 different subunits (α1-7
and β1-7) but exists as different subtypes depending on the cell type. In immune cells, for …
and β1-7) but exists as different subtypes depending on the cell type. In immune cells, for …