Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …
A precision environmental health approach to prevention of human disease
Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …
Role of endocrine-disrupting chemicals in the pathogenesis of non-alcoholic fatty liver disease: a comprehensive review
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder,
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …
affecting around 25% of the population worldwide. It is a complex disease spectrum, closely …
Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure
Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as
environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the …
environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the …
Kidney and epigenetic mechanisms of salt-sensitive hypertension
W Kawarazaki, T Fujita - Nature Reviews Nephrology, 2021 - nature.com
Dietary salt intake increases blood pressure (BP) but the salt sensitivity of BP differs
between individuals. The interplay of ageing, genetics and environmental factors, including …
between individuals. The interplay of ageing, genetics and environmental factors, including …
New insights into the epigenetic regulation of inflammatory bowel disease
J Xu, H Xu, M Yang, Y Liang, Q Peng… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the colonic mucosa.
Environmental factors, genetics, intestinal microbiota, and the immune system are all …
Environmental factors, genetics, intestinal microbiota, and the immune system are all …
The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis
MV Bariani, R Rangaswamy, H Siblini… - Current Opinion in …, 2020 - journals.lww.com
While research on EDCs and fibroids is still evolving, recent evidence suggests EDC
exposures may contribute to fibroid risk and progression. Further research is needed to …
exposures may contribute to fibroid risk and progression. Further research is needed to …
Windows of opportunity: Ocean warming shapes temperature‐sensitive epigenetic reprogramming and gene expression across gametogenesis and embryogenesis in …
Rapid climate change is placing many marine species at risk of local extinction. Recent
studies show that epigenetic mechanisms (eg DNA methylation, histone modifications) can …
studies show that epigenetic mechanisms (eg DNA methylation, histone modifications) can …
Developmental reprogramming of myometrial stem cells by endocrine disruptor linking to risk of uterine fibroids
Background The stage, when tissues and organs are growing, is very vulnerable to
environmental influences, but it's not clear how exposure during this time causes changes to …
environmental influences, but it's not clear how exposure during this time causes changes to …
Metals exposures and DNA methylation: current evidence and future directions
ER Elkin, C Higgins, MT Aung, KM Bakulski - Current environmental health …, 2022 - Springer
Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …