Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

Myeloid cells are pivotal within the immunosuppressive tumour microenvironment. The
accumulation of tumour-modified myeloid cells derived from monocytes or neutrophils …

Myeloid-derived suppressor cells (MDSCs) are one of the most discussed biological entities
in immunology. While the context and classification of this group of cells has evolved …

Summary Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract
infection, however, a subset of patients progress to severe disease and respiratory failure …

Immune checkpoint inhibitor (ICI) therapy is effective against many cancers for a subset of
patients; a large percentage of patients remain unresponsive to this therapy. One …

Chronic inflammation and immune responses are two core element that characterize the
tumor microenvironment. A large number of immune/inflammatory cells (including tumor …

New evidence has challenged the outdated dogma that neutrophils are a homogeneous
population of short-lived cells. Although neutrophil subpopulations with distinct functions …

Dendritic cells (DCs) and monocytes are crucial mediators of innate and adaptive immune
responses during viral infection, but misdirected responses by these cells may contribute to …

Background Myeloid-derived suppressor cells (MDSC) are a functional myeloid cell subset
that includes myeloid cells with immune suppressive properties. The presence of MDSC has …

Objective The role of N6-methyladenosine (m6A) in tumour immune microenvironment
(TIME) remains understudied. Here, we elucidate function and mechanism of YTH N6 …