The complement system has historically been entertained as a fluid-phase, hepatically
derived system which protects the intravascular space from encapsulated bacteria …

With the advancement in research in the field of the complement system, a more
comprehensive understanding developed about the complement system's role in the life …

Background & Aims Cirrhosis-associated immune dysfunction (CAID) affects both innate and
adaptive immunity. This study investigated the complement system, immunoglobulins, and …

Background & Aims Liver fibrosis represents a hallmark of most chronic liver diseases (CLD)
triggered by recurrent liver injury and subsequent myofibroblast transdifferentiations of …

Background and Aims Given the lack of effective therapies and high mortality in acute
alcohol‐associated hepatitis (AH), it is important to develop rationally designed biomarkers …

Objective To explore the relationship between immunoglobulin A (IgA), complement C4, and
liver fibrosis (LF) progression (LFP) in patients with chronic hepatitis B (CHB). Methods This …

Complement is usually seen to largely originate from the liver to accomplish its tasks
systemically–its return to the production site has long been underestimated. Recent …

Severe bacterial infection is a major complication causing morbidity and mortality in β‐
thalassaemia/HbE patients. Innate immunity constitutes the first line of defence against …

Background: Spontaneous bacterial peritonitis (SBP) is a severe and often fatal infection in
patients with decompensated cirrhosis and ascites. The only cure for SBP is antibiotic …

Background and Aims Patients with chronic hepatitis B virus infection (CBI) with concurrent
nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common in clinical …