Arsenic is widely present in the environment and is associated with various population
health risks including cancers. Arsenic exposure at environmentally relevant levels …

Arsenic trioxide (ATO) is a frontline chemotherapy drug used in the therapy of acute
promyelocytic leukemia. However, the clinical use of ATO is hindered by its cardiotoxicity …

Lung cancer is the second most common cancer diagnosed and is the leading cause of
cancer-related deaths globally. Even though there are established lung cancer treatment …

The survival benefits of sorafenib treatment for patients with hepatocellular carcinoma (HCC)
are limited due to drug resistance and side effects. Therefore, combinations of sorafenib with …

Background: Promoter hyper-methylation of tumor suppressor genes is a common event that
occurs in cancer. As methylation is a reversible modification, agents capable of reversing an …

Background Chordoma, slow growing bone tumours originating from remnants of the
notochord, leave affected patients with a median survival of six years. The high recurrence …

Background: The most common form of human primary brain tumor resistant to treatment is
glioblastoma multiforme. For brain tumors, it is essential to optimize the treatment regimen …

Background: Breast cancer is the second leading cause of cancer death after lung cancer.
Discovering molecular biomarkers is necessary for disease management that includes …

The present study aimed to evaluate the cellular and molecular effects of low concentrations
of the flavonoid, fisetin, on K562 human chronic myeloid leukemia cells, in the context of …

Malignant growth is a significant weight of illness around the world. Internationally, one in
every five men and one out of six women will become a potential victim of malignancy prior …