[HTML][HTML] Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

W Ornatowski, Q Lu, M Yegambaram, AE Garcia… - Redox biology, 2020 - Elsevier
The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

[HTML][HTML] Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases

G Cavalli, S Colafrancesco, G Emmi, M Imazio… - Autoimmunity …, 2021 - Elsevier
Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

[HTML][HTML] First evidence of microplastics isolated in European citizens' lower airway

C Baeza-Martínez, S Olmos, M González-Pleiter… - Journal of Hazardous …, 2022 - Elsevier
Microplastics (MPs) have been detected in all environmental locations, including the
atmosphere. However, few studies have investigated the presence of airborne MPs in the …

Update on the pathogenesis of chronic obstructive pulmonary disease

A Agustí, JC Hogg - New England Journal of Medicine, 2019 - Mass Medical Soc
Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

The cellular and physiological basis for lung repair and regeneration: past, present, and future

MC Basil, J Katzen, AE Engler, M Guo, MJ Herriges… - Cell stem cell, 2020 - cell.com
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …

[HTML][HTML] Tuberculosis and lung damage: from epidemiology to pathophysiology

S Ravimohan, H Kornfeld, D Weissman… - European respiratory …, 2018 - Eur Respiratory Soc
A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …

An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation

MA Spruit, SJ Singh, C Garvey… - American journal of …, 2013 - atsjournals.org
Background: Pulmonary rehabilitation is recognized as a core component of the
management of individuals with chronic respiratory disease. Since the 2006 American …

Role of Nrf2 and its activators in respiratory diseases

Q Liu, Y Gao, X Ci - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

COPD and multimorbidity: recognising and addressing a syndemic occurrence

LM Fabbri, BR Celli, A Agustí, GJ Criner… - The Lancet …, 2023 - thelancet.com
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …

Endobronchial valves for emphysema without interlobar collateral ventilation

K Klooster, NHT Ten Hacken, JE Hartman… - New England journal …, 2015 - Mass Medical Soc
Background Bronchoscopic lung-volume reduction with the use of one-way endobronchial
valves is a potential treatment for patients with severe emphysema. To date, the benefits …