Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics

C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …

Assessment of copy number variation in genes related to drug resistance in Plasmodium vivax and Plasmodium falciparum isolates from the Brazilian Amazon and a …

GL Costa, LC Amaral, CJF Fontes, LH Carvalho… - Malaria journal, 2017 - Springer
Background Parasite resistance to anti-malarials represents a great obstacle for malaria
elimination. The majority of studies have investigated the association between single …

Transmission dynamics of co-endemic Plasmodium vivax and P. falciparum in Ethiopia and prevalence of antimalarial resistant genotypes

E Lo, E Hemming-Schroeder, D Yewhalaw… - PLoS neglected …, 2017 - journals.plos.org
Ethiopia is one of the few African countries where Plasmodium vivax is co-endemic with P.
falciparum. Malaria transmission is seasonal and transmission intensity varies mainly by …

Using Amplicon Deep Sequencing to Detect Genetic Signatures of Plasmodium vivax Relapse

JT Lin, NJ Hathaway, DL Saunders… - The Journal of …, 2015 - academic.oup.com
Plasmodium vivax infections often recur due to relapse of hypnozoites from the liver. In
malaria-endemic areas, tools to distinguish relapse from reinfection are needed. We applied …

Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon

SR Silva, ACG Almeida, GAV da Silva, R Ramasawmy… - Malaria journal, 2018 - Springer
Abstract Background The resistance of Plasmodium vivax to chloroquine has become an
obstacle to control strategies based on the use of anti-malarials. The current study …

[HTML][HTML] Genetic diversity and molecular evolution of Plasmodium vivax Duffy binding protein and merozoite surface protein-1 in northwestern Thailand

P Tapaopong, G da Silva, S Chainarin… - Infection, Genetics and …, 2023 - Elsevier
The local diversity and population structure of malaria parasites vary across different regions
of the world, reflecting variations in transmission intensity, host immunity, and vector species …

Whole Genome Sequencing of Field Isolates Reveals Extensive Genetic Diversity in Plasmodium vivax from Colombia

DJ Winter, MA Pacheco, AF Vallejo… - PLoS neglected …, 2015 - journals.plos.org
Plasmodium vivax is the most prevalent malarial species in South America and exerts a
substantial burden on the populations it affects. The control and eventual elimination of P …

Novel highly-multiplexed AmpliSeq targeted assay for Plasmodium vivax genetic surveillance use cases at multiple geographical scales

JH Kattenberg, HV Nguyen, HL Nguyen… - Frontiers in Cellular …, 2022 - frontiersin.org
Although the power of genetic surveillance tools has been acknowledged widely, there is an
urgent need in malaria endemic countries for feasible and cost-effective tools to implement …

[HTML][HTML] The prevalence of molecular markers of drug resistance in Plasmodium vivax from the border regions of Thailand in 2008 and 2014

K Tantiamornkul, T Pumpaibool, J Piriyapongsa… - International Journal for …, 2018 - Elsevier
The prevalence of Plasmodium vivax is increasing in the border regions of Thailand; one
potential problem confounding the control of malaria in these regions is the emergence and …

[HTML][HTML] Multidisciplinary investigations of sustained malaria transmission in the Greater Mekong Subregion

L Cui, J Sattabongkot, PL Aung… - The American journal …, 2022 - ncbi.nlm.nih.gov
In the course of malaria elimination in the Greater Mekong Subregion (GMS), malaria
epidemiology has experienced drastic spatiotemporal changes with residual transmission …