Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Its
worldwide prevalence is rapidly increasing and is currently estimated at 24%. NAFLD is …

Choline, an essential dietary nutrient for humans, is required for the synthesis of the
neurotransmitter, acetylcholine, the methyl group donor, betaine, and phospholipids; and …

Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …

Cardiovascular disease (CVD) is the leading cause of death in the United States. For years,
dietary cholesterol was implicated in increasing blood cholesterol levels leading to the …

Emerging evidence suggests that microbes resident in the human intestine represent a key
environmental factor contributing to obesity-associated disorders. Here, we demonstrate that …

Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord
involvement. The most clinically significant subtype is myelomeningocele (open spina …

The foundations of neurodevelopment across an individual's lifespan are established in the
first 1000 days of life (2 years). During this period an adequate supply of nutrients are …

Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its
derivatives serve as components of structural lipoproteins, blood and membrane lipids, and …

Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

We studied associations between prenatal and early postnatal choline intake, brain
development, and neurocognitive function of children. We conducted a systematic review …