Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Perioperative organ injury is among the leading causes of morbidity and mortality of surgical
patients. Among different types of perioperative organ injury, acute kidney injury occurs …

Rationale: Recent retrospective evidence suggests the efficacy of early norepinephrine
administration during resuscitation; however, prospective data to support this assertion are …

Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

Objective International guidelines recommend dopamine or norepinephrine as first-line
vasopressor agents in septic shock. Phenylephrine, epinephrine, vasopressin and …

Introduction This study investigated the incidence of delayed norepinephrine administration
following the onset of septic shock and its effect on hospital mortality. Methods We …

In patients with acute kidney injury (AKI), optimization of systemic haemodynamics is central
to the clinical management. However, considerable debate exists regarding the efficacy …

Objectives: There has long-been controversy about the possible superiority of
norepinephrine compared to dopamine in the treatment of shock. The objective was to …

Intravenous fluids are widely administered to patients who have, or are at risk of, acute
kidney injury (AKI). However, deleterious consequences of overzealous fluid therapy are …

Effects of perfusion pressure on tissue perfusion in septic... : Critical Care Medicine Effects of
perfusion pressure on tissue perfusion in septic shock : Critical Care Medicine SCCM Pediatric …