The epidemiology and aetiology of drug‐induced liver injury (DILI) vary across different
countries and populations. Overall, DILI is rare in the general population but has become …

Background: A large number of idiosyncratic drug induced liver injury (iDILI) and herb
induced liver injury (HILI) cases of variable quality has been published but some are a …

Excess accumulation of mitochondrial reactive oxygen species (mtROS) is a key target for
inhibiting pyroptosis‐induced inflammation and tissue damage. However, targeted delivery …

Acute liver failure (ALF) is a rare and specific form of severe hepatic dysfunction
characterized by coagulopathy and hepatic encephalopathy in a patient with no known liver …

Acetaminophen (APAP), one of the most common antipyretic analgesics, which is safe at
therapeutic dose, cause acute liver injury and even death at overdose. However, the …

Background & Aims Acetaminophen (APAP)-induced acute liver injury (ALI) is a global
health issue characterised by an incomplete understanding of its pathogenesis and …

Acute liver failure caused by drug overdose is a significant clinical problem in developed
countries. Acetaminophen (APAP), a widely used analgesic and antipyretic drug, but its …

Background Drug induced bile duct injury is a frequently observed clinical problem leading
to a wide range of pathological features. During the past decades, several agents have been …

Excessive acetaminophen (APAP) can induce neutrophil activation and hepatocyte death.
Along with hepatocyte dysfunction and death, NETosis (a form of neutrophil-associated …

Drug-induced liver injury (DILI) is a serious clinical disease associated with reactive oxygen
species (ROS) burst and subsequent inflammatory responses. However, traditional …