The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …

The development of effective treatments for cancers requires investigations for a more
detailed and comprehensive understanding of the basic cellular mechanisms involved in …

Breast cancer exhibits the highest global incidence among all tumor types. Regardless of
the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of …

Evidence is increasing on the crucial role of the extracellular matrix (ECM) in breast cancer
progression, invasion and metastasis with almost all mortality cases owing to metastasis …

Anoikis is a type of programmed cell death induced by detachment from the extracellular
matrix. In cancer cells, anoikis resistance is essential for cancer cell survival in blood …

Within the tumor microenvironment, the fight between the immune system and cancer
influences tumor transformation. Metastasis formation is an important stage in the …

For the past two decades, the study of alternative splicing (AS) and its involvement in plant
development and stress response has grown in popularity. Only recently however, has the …

Anchorage-independent survival after intravasation of cancer cells from the primary tumor
site represents a critical step in metastasis. Here, we reveal new insights into how MUC13 …

By regulating transcript isoform expression levels, alternative splicing provides an additional
layer of protein control. Recent studies show evidence that cancer cells use different splicing …