The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …

Drug repositioning and repurposing can enhance traditional drug development efforts and
could accelerate the identification of new treatments for individuals with Alzheimer disease …

Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

Neurodegenerative disorders like Parkinson's disease, Alzheimer's disease, or amyotrophic
lateral sclerosis are affecting a rapidly increasing population worldwide. While common …

The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell
morphology, with a role in several essential cellular processes, including cell migration and …

Histamine-induced vascular leakage is an integral component of many highly prevalent
human diseases, including allergies, asthma and anaphylaxis. Yet, how histamine induces …

Adult neural stem cells (NSCs) play important roles in learning and memory and are
negatively impacted by neurological disease. It is known that biochemical and genetic …

Non-muscle myosin 2A (NM2A) is a motor cytoskeletal enzyme with crucial importance from
the early stages of development until adulthood. Due to its capacity to convert chemical …

Introduction Synapse loss is the structural correlate of the cognitive decline indicative of
dementia. In the brains of Alzheimer's disease sufferers, amyloid β (Aβ) peptides aggregate …

The brain has a remarkable but underappreciated capacity to limit memory formation and
expression. The term" memory suppressor gene" was coined in 1998 as an attempt to …