Innate immune responses to trauma

M Huber-Lang, JD Lambris, PA Ward - Nature immunology, 2018 - nature.com
Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Biocatalytic and antioxidant nanostructures for ROS scavenging and biotherapeutics

L Wang, B Zhu, Y Deng, T Li, Q Tian… - Advanced Functional …, 2021 - Wiley Online Library
In human systems, reactive oxygen species (ROS) significantly affect different physiological
activities and play critical roles in diverse living processes. It is widely known that excessive …

Prehospital tranexamic acid for severe trauma

… and the ANZICS Clinical Trials Group - … England Journal of …, 2023 - Mass Medical Soc
Background Whether prehospital administration of tranexamic acid increases the likelihood
of survival with a favorable functional outcome among patients with major trauma and …

Transplantation of human mesenchymal stem-cell-derived exosomes immobilized in an adhesive hydrogel for effective treatment of spinal cord injury

L Li, Y Zhang, J Mu, J Chen, C Zhang, H Cao, J Gao - Nano letters, 2020 - ACS Publications
Spinal cord injury is among the most fatal diseases. The complicated inhibitory
microenvironment requires comprehensive mitigation. Exosomes derived from …

A MnO2 Nanoparticle-Dotted Hydrogel Promotes Spinal Cord Repair via Regulating Reactive Oxygen Species Microenvironment and Synergizing with …

L Li, B Xiao, J Mu, Y Zhang, C Zhang, H Cao, R Chen… - ACS …, 2019 - ACS Publications
Spinal cord injury (SCI) is one of the most debilitating injuries, and transplantation of stem
cells in a scaffold is a promising strategy for treatment. However, stem cell treatment of SCI …

Long-term functional, psychological, emotional, and social outcomes in survivors of firearm injuries

MA Vella, A Warshauer, G Tortorello… - JAMA …, 2020 - jamanetwork.com
Importance The outcomes of firearm injuries in the United States are devastating. Although
firearm mortality and costs have been investigated, the long-term outcomes after surviving a …

Factors associated with long-term outcomes after injury: results of the functional outcomes and recovery after trauma emergencies (FORTE) multicenter cohort study

AH Haider, JP Herrera-Escobar, SS Al Rafai… - Annals of …, 2020 - journals.lww.com
Objective: The aim of this study was to determine factors associated with patient-reported
outcomes, 6 to 12 months after moderate to severe injury. Summary of Background Data …

A conductive dual-network hydrogel composed of oxidized dextran and hyaluronic-hydrazide as BDNF delivery systems for potential spinal cord injury repair

F Huang, T Chen, J Chang, C Zhang, F Liao… - International Journal of …, 2021 - Elsevier
Spinal cord injury (SCI) often causes neuronal death and axonal degeneration. In this study,
we report a new strategy for preparing injectable and conductive polysaccharides-based …

The social vulnerability index and long-term outcomes after traumatic injury

JP Herrera-Escobar, T Uribe-Leitz, J Wang… - Annals of …, 2022 - journals.lww.com
Objective: The aim of this study was to evaluate the Social Vulnerability Index (SVI) as a
predictor of long-term outcomes after injury. Background: The SVI is a measure used in …

Thoracic injuries in trauma patients: epidemiology and its influence on mortality

A Lundin, SK Akram, L Berg, KE Göransson… - Scandinavian journal of …, 2022 - Springer
Background Thoracic injuries are common among trauma patients. Studies on trauma
patients with thoracic injuries have reported considerable differences in morbidity and …