Before the first description of hay fever in 1870, there was very little awareness of allergic
disease, which is actually similar to the situation in prehygiene villages in Africa today. The …

Inflammation is a stereotypical physiological response to infections and tissue injury; it
initiates pathogen killing as well as tissue repair processes and helps to restore …

Background: When using the change-in-estimate criterion, a cutoff of 10% is commonly used
to identify confounders. However, the appropriateness of this cutoff has never been …

Introduction The 6-min walking distance (6MWD) test is a useful tool to obtain a measure of
functional exercise capacity. However, reference equations have been mainly based on …

Epidemiological studies first demonstrated the association between obesity and asthma and
they have begun to provide additional evidence to support causality: a dose–effect …

Objective We assessed associations between physical activity and lung function, and its
decline, in the prospective population-based European Community Respiratory Health …

Background Childhood asthma is a global problem affecting the respiratory health of
children. Physical activity (PA) plays a role in the relationship between asthma and …

Rationale: The potential role of physical activity in preventing asthma exacerbations is
unknown. Objectives: To investigate the longitudinal association between regular physical …

BACKGROUND The growing epidemics of obesity and asthma are major public health
concerns. Although asthma-obesity links are widely studied, the effects of weight loss on …

During dynamic exercise, the healthy pulmonary system faces several major challenges,
including decreases in mixed venous oxygen content and increases in mixed venous …