Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications

S Iqbal, M Blenner, A Alexander-Bryant… - …, 2020 - ACS Publications
Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …

Self-assembled polymeric vesicles: Focus on polymersomes in cancer treatment

F Araste, A Aliabadi, K Abnous, SM Taghdisi… - Journal of Controlled …, 2021 - Elsevier
The progress in advanced materials using nanoscale components can be conducted by an
innovative idea involving combining nanotechnology approaches with supramolecular …

Polymer vesicles: modular platforms for cancer theranostics

F Wang, J Xiao, S Chen, H Sun, B Yang… - Advanced …, 2018 - Wiley Online Library
As an emerging field that is receiving an increasing amount of interest, theranostics is
becoming increasingly important in the field of nanomedicine. Among the various smart …

Biomolecules turn self-assembling amphiphilic block co-polymer platforms into biomimetic interfaces

S Yorulmaz Avsar, M Kyropoulou, S Di Leone… - Frontiers in …, 2019 - frontiersin.org
Biological membranes constitute an interface between cells and their surroundings and form
distinct compartments within the cell. They also host a variety of biomolecules that carry out …

Current paradigms in employing self-assembled structures: Drug delivery implications with improved therapeutic potential

A Sharma, M Singh, V Sharma, A Vashishth… - Colloids and Surfaces B …, 2024 - Elsevier
Recent efforts have focused on developing improved drug delivery systems with enhanced
therapeutic efficacy and minimal side effects. Micelles, self-assembled from amphiphilic …

Advances in Intracellular and On‐Surface Polymerization in Living Cells: Implications for Nanobiomedicines

P Laskar, OP Varghese… - Advanced NanoBiomed …, 2023 - Wiley Online Library
The cellular environment offers some unique features to carry out polymerizations under
controlled conditions. Polymerization of monomers in cellular compartments and on the …

Co-delivery of hydrophilic and hydrophobic drugs by micelles: a new approach using drug conjugated PEG–PCLNanoparticles

H Danafar, K Rostamizadeh, S Davaran… - Drug development and …, 2017 - Taylor & Francis
Co-delivery strategy has been proposed to minimize the amount of each drug and to
achieve the synergistic effect for cancer therapies. A conjugate of the antitumor drug …

Hollow and vesicle particles from macromolecules with amphiphilic monomer units

VV Vasilevskaya, EN Govorun - Polymer Reviews, 2019 - Taylor & Francis
Amphiphilic monomer units contain both hydrophobic and hydrophilic groups. They are
characterized by affinity and antagonism simultaneously to both polar and nonpolar …

REDOX responsive fluorescence active glycopolymer based nanogel: A potential material for targeted anticancer drug delivery

K Bhattacharya, SL Banerjee, S Das… - ACS Applied Bio …, 2019 - ACS Publications
A well-defined glycopolymer based fluorescence active nanogel has been prepared via the
combination of reversible addition–fragmentation chain transfer (RAFT) polymerization and …

Thermoresponsive gelation of amphiphilic random copolymer micelles in water

M Shibata, T Terashima, T Koga - Macromolecules, 2021 - ACS Publications
Herein, we developed thermoresponsive gelation systems of amphiphilic random copolymer
micelles in water. To establish the design of micelle nanodomains for the physical gels, we …