Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality
worldwide. Its complexity is influenced by various signal transduction networks that govern …

Boron neutron capture therapy (BNCT) is a potential cancer radiotherapeutic modality,
which takes advantage of the neutron capture response that occurs when boron (10 B) is …

Background Inhibiting vascular endothelial growth factor (VEGF) function can improve the
efficacy of immunotherapy by modulating the tumor immune microenvironment. AK112 is the …

Angiogenesis is an essential process involved in various physiological, including
placentation, and pathological, including cancer and endometriosis, processes. Melatonin …

Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Abstract Development of new anticancer drugs has resulted in improved mortality rates and
5-year survival rates in patients with cancer. However, many of the modern chemotherapies …

Abstract Serotonin (5-hydroxytryptamine or 5-HT) once most extensively studied as a
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …

Tumor angiogenesis is a key event that governs tumor progression and metastasis. It is
controlled by the complicated and coordinated actions of pro-angiogenic factors and their …

Pancreatic ductal adenocarcinoma (PDAC) is a KRAS-driven cancer with a high incidence
of metastasis and an overall poor prognosis. Previous work in a genetically engineered …

Cancer metastasis is one of the leading causes of death worldwide, motivating research into
identifying new methods of preventing cancer metastasis. Recently there has been …