Diabetic kidney disease is expected to increase rapidly over the coming decades with rising
prevalence of diabetes worldwide. Current measures of kidney function based on …

Chronic kidney disease (CKD) is one of the increasingly serious public health concerns
worldwide; the global burden of CKD is increasingly due to high morbidity and mortality. At …

Purpose: Quercetin, the most widely distributed flavonoid, has been shown to have multiple
properties and beneficial effects on various metabolic diseases. Thus, our aim was to …

Background Diabetic nephropathy (DN), the formation of albuminuria, is one of the most
important complications seen in diabetic patients. IL-37, an inhibitor of congenital …

Objective—Cyclophilin A (CyPA) is secreted from vascular smooth muscle cells,
inflammatory cells, and activated platelets in response to oxidative stress. We have recently …

Dyslipidemia and inflammation have great roles in the development of diabetic nephropathy
(DN). Oleanolic acid (OA) is a natural triterpenoid that possesses multiple pharmacological …

Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells.
Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular …

Diabetic nephropathy (DN) is one of the most severe chronic kidney diseases in diabetes
and is the main cause of end-stage renal disease (ESRD). Protocatechuic aldehyde (PCA) …

To find the associations of circulating cyclophilin A (CyP A) and CD147/EMMPRIN with renal
outcomes in type 2 diabetes patients and possible pathogenesis involved. Total 131 patients …

Background Currently, microalbuminuria is the gold standard for detection and prediction of
diabetic nephropathy (DN). However, microalbuminuria appears once significant kidney …