Cross-species transmission, evolution and zoonotic potential of coronaviruses

Q Li, T Shah, B Wang, L Qu, R Wang, Y Hou… - Frontiers in Cellular …, 2023 - frontiersin.org
Coronaviruses (CoVs) continuously evolve, crossing species barriers and spreading across
host ranges. Over the last two decades, several CoVs (HCoV-229E, HCoV-NL63, HCoV …

PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease

M Duhalde Vega, D Olivera, G Gastão Davanzo… - Science …, 2022 - science.org
Severe COVID-19 is associated with hyperinflammation and weak T cell responses against
SARS-CoV-2. However, the links between those processes remain partially characterized …

T cell responses to SARS-CoV-2 in humans and animals

SS Mattoo, J Myoung - Journal of Microbiology, 2022 - Springer
Abstract SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody
responses against SARS-CoV-2 have been given a lot of attention. However, the …

Activation of TCA cycle restrains virus-metabolic hijacking and viral replication in mouse hepatitis virus-infected cells

SR Lee, JY Roh, J Ryu, HJ Shin, EJ Hong - Cell & bioscience, 2022 - Springer
Background One of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), has caused coronavirus disease 2019 (COVID-19) pandemic and threatened …

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors

NL Inniss, J Kozic, F Li, M Rosas-Lemus… - ACS infectious …, 2023 - ACS Publications
A collaborative, open-science team undertook discovery of novel small molecule inhibitors
of the SARS-CoV-2 nsp16-nsp10 2′-O-methyltransferase using a high throughput …

The integral membrane protein ZMPSTE24 protects cells from SARS-CoV-2 spike-mediated pseudovirus infection and syncytia formation

K Shilagardi, ED Spear, R Abraham, DE Griffin… - MBio, 2022 - Am Soc Microbiol
ABSTRACT COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) has had a devastating impact on global public health, emphasizing the …

Multi-organ histopathological changes in a mouse hepatitis virus model of COVID-19

MJ Paidas, AB Mohamed, MD Norenberg, A Saad… - Viruses, 2021 - mdpi.com
Infection with SARS-CoV-2, the virus responsible for the global COVID-19 pandemic, causes
a respiratory illness that can severely impact other organ systems and is possibly …

Assessment of GO-based protein interaction affinities in the large-scale human–coronavirus family interactome

SS Bandyopadhyay, AK Halder, S Saha, P Chatterjee… - Vaccines, 2023 - mdpi.com
SARS-CoV-2 is a novel coronavirus that replicates itself via interacting with the host
proteins. As a result, identifying virus and host protein-protein interactions could help …

Remdesivir Derivative VV116 Is a Potential Broad-Spectrum Inhibitor of Both Human and Animal Coronaviruses

W Liu, M Zhang, C Hu, H Song, Y Mei, Y Liu, Q Zhang - Viruses, 2023 - mdpi.com
Coronaviruses represent a significant threat to both human and animal health,
encompassing a range of pathogenic strains responsible for illnesses, from the common …

[HTML][HTML] Hydrophobic cellulose-based and non-woven fabrics coated with mesoporous TiO2 and their virucidal properties under indoor light

DCS Souza, SM Amorim, RD Cadamuro… - Carbohydrate Polymer …, 2022 - Elsevier
Antiviral hydrophobic cellulose-based cotton or non-woven fabrics containing mesoporous
TiO 2 particles were developed for potential use in healthcare and in other contaminated …