[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

Role of p38/MAPKs in Alzheimer's disease: implications for amyloid beta toxicity targeted therapy

G Kheiri, M Dolatshahi, F Rahmani… - Reviews in the …, 2018 - degruyter.com
A myriad of environmental and genetic factors, as well as the physiologic process of aging,
contribute to Alzheimer's disease (AD) pathology. Neuroinflammation is and has been a …

Astaxanthin impact on brain: health potential and market perspective

SA Cunha, S Borges, S Baptista-Silva… - Critical Reviews in …, 2023 - Taylor & Francis
Nowadays, there is an emergent interest in new trend-driven biomolecules to improve health
and wellbeing, which has become an interesting and promising field, considering their high …

[HTML][HTML] Carotenoids as novel therapeutic molecules against neurodegenerative disorders: Chemistry and molecular docking analysis

J Lakey-Beitia, J Kumar D, ML Hegde… - International Journal of …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most devastating neurodegenerative disorder that affects the
aging population worldwide. Endogenous and exogenous factors are involved in triggering …

[HTML][HTML] Propentofylline improves thiol-based antioxidant defenses and limits lipid peroxidation following gliotoxic injury in the rat brainstem

DEM Baliellas, MP Barros, CV Vardaris, M Guariroba… - Biomedicines, 2023 - mdpi.com
Propentofylline (PROP) is a methylated xanthine compound that diminishes the activation of
microglial cells and astrocytes, which are neuronal cells strongly associated with many …

[HTML][HTML] The putative role of astaxanthin in neuroinflammation modulation: Mechanisms and therapeutic potential

S Wang, X Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
Neuroinflammation is a protective mechanism against insults from exogenous pathogens
and endogenous cellular debris and is essential for reestablishing homeostasis in the brain …

Natural Carotenoids as Neuroprotective Agents for Alzheimer's Disease: An Evidence-Based Comprehensive Review

Z Batool, JH Chen, Y Gao, LW Lu, H Xu… - Journal of Agricultural …, 2022 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disorder of an ever-increasing aging
population with various pathological features such as β-amyloid (Aβ) aggregation, oxidative …

Neuroprotective and antioxidant effects of docosahexaenoic acid (DHA) in an experimental model of multiple sclerosis

A Muñoz-Jurado, BM Escribano, A Galván… - The Journal of …, 2024 - Elsevier
Multiple sclerosis (MS) is a chronic demyelinating disease, whose etiology is not yet fully
understood, although there are several factors that can increase the chances of suffering …

DHA, EPA and their combination at various ratios differently modulated Aβ25-35-induced neurotoxicity in SH-SY5Y cells

YP Zhang, RE Brown, PC Zhang, YT Zhao… - … and Essential Fatty …, 2018 - Elsevier
Omega-3 polyunsaturated fatty acids (n− 3 PUFAs), docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA), have been reported to prevent neurodegenerative diseases …

Krill oil protects PC12 cells against methamphetamine-induced neurotoxicity by inhibiting apoptotic response and oxidative stress

Q Xiong, Q Ru, X Tian, M Zhou, L Chen, Y Li, C Li - Nutrition Research, 2018 - Elsevier
Methamphetamine (METH) exposure can cause severe effects to the nervous system;
however, the underlying molecular mechanism of neurotoxicity caused by METH is still …