Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the
apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep …

Abstract Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …

The gut microbiota maintains a symbiotic relationship with the host and regulates several
important functions including host metabolism, immunity, and intestinal barrier function …

Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …

Sleep disruption appears to be a core component of Alzheimer's disease (AD) and its
pathophysiology. Signature abnormalities of sleep emerge before clinical onset of AD …

Most animals require sleep, and sleep loss induces serious pathophysiological
consequences, including death. Previous experimental approaches for investigating sleep …

Sepsis is life-threatening and often leads to acute brain damage. Dexmedetomidine, an α2-
adrenoceptor agonist, has been reported to possess neuroprotective effects against various …

The function of sleep remains one of biology's biggest mysteries. A solution to this problem
is likely to come from a better understanding of sleep homeostasis, and in particular of the …