The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Dipeptidyl-peptidase 4 (DPP4) is a glycoprotein of 110 kDa, which is ubiquitously expressed
on the surface of a variety of cells. This exopeptidase selectively cleaves N-terminal …

A medical syndrome is a clustering of clinical findings that occur together more often than
would be expected by chance. The constellation of components that make up the metabolic …

There have been considerable recent advances towards a better understanding of the
complex cellular and molecular network underlying liver fibrogenesis. Recent data indicate …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China
placed emphasis on liver involvement during infection. This review discusses the underlying …

By now, non-alcoholic fatty liver disease (NAFLD) is considered to be among the most
common liver diseases world-wide. NAFLD encompasses a broad spectrum of pathological …

Alcoholic liver disease (ALD) is a global public health challenge due to the high incidence
and lack of effective therapeutics. Evidence from animal studies and ALD patients has …

Background & Aims We investigated the effects of the fatty acid–bile acid conjugate 3β-
arachidyl-amido, 7α-12α-dihydroxy, 5β-cholan-24-oic acid (Aramchol; Trima Israel …