Recent advances in lab-on-a-chip for biosensing applications

JP Lafleur, A Jönsson, S Senkbeil, JP Kutter - Biosensors and …, 2016 - Elsevier
The marriage of highly sensitive biosensor designs with the versatility in sample handling
and fluidic manipulation offered by lab-on-a-chip systems promises to yield powerful tools …

Microfabricated electrochemical sensing devices

F Sassa, GC Biswas, H Suzuki - Lab on a Chip, 2020 - pubs.rsc.org
Electrochemistry provides possibilities to realize smart microdevices of the next generation
with high functionalities. Electrodes, which constitute major components of electrochemical …

Chemical analysis of single cells

R Trouillon, MK Passarelli, J Wang, ME Kurczy… - Analytical …, 2013 - ACS Publications
Many biological systems contain an ensemble of cells with heterogeneous chemistry;
therefore, it is important to analyze them on an individual basis in order to elucidate the role …

Overview of optical and electrochemical alkaline phosphatase (ALP) biosensors: Recent approaches in cells culture techniques

T Balbaied, E Moore - Biosensors, 2019 - mdpi.com
Alkaline phosphatase (ALP), which catalyzes the dephosphorylation process of proteins,
nucleic acids, and small molecules, can be found in a variety of tissues (intestine, liver …

Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

M Şen, K Ino, J Ramón-Azcón, H Shiku, T Matsue - Lab on a Chip, 2013 - pubs.rsc.org
We present a chip device with an array of 900 gourd-shaped microwells designed to pair
single cells of different types. The device consists of interdigitated array (IDA) electrodes and …

Redox-capacitor to connect electrochemistry to redox-biology

E Kim, WT Leverage, Y Liu, IM White, WE Bentley… - Analyst, 2014 - pubs.rsc.org
It is well-established that redox-reactions are integral to biology for energy harvesting
(oxidative phosphorylation), immune defense (oxidative burst) and drug metabolism (phase I …

High-density droplet microarray of individually addressable electrochemical cells

H Zhang, T Oellers, W Feng, T Abdulazim… - Analytical …, 2017 - ACS Publications
Microarray technology has shown great potential for various types of high-throughput
screening applications. The main read-out methods of most microarray platforms, however …

Non-toxic flexible screen-printed MWCNT-based electrodes for non-invasive biomedical applications

M Şen, M Oğuz, İ Avcı - Talanta, 2024 - Elsevier
Here, a non-toxic, flexible, low-cost, and disposable multiwalled carbon nanotube (MWCNT)-
based screen-printed electrode (SPE) was developed for non-invasive health monitoring …

Bioelectrochemical applications of microelectrode arrays in cell analysis and engineering

K Ino, H Shiku, T Matsue - Current Opinion in Electrochemistry, 2017 - Elsevier
This review summarizes recent advances in cell-related applications of microelectrode
arrays. In the review, we discuss devices featuring multiple sensors incorporated into a small …

LSI-based amperometric sensor for real-time monitoring of embryoid bodies

M Şen, K Ino, KY Inoue, T Arai, T Nishijo, A Suda… - Biosensors and …, 2013 - Elsevier
A large scale integration (LSI)-based amperometric sensor is used for electrochemical
evaluation and real-time monitoring of the alkaline phosphatase (ALP) activity of mouse …