Parallel computing in genomic research: advances and applications

K Ocaña, D de Oliveira - Advances and applications in …, 2015 - Taylor & Francis
Today's genomic experiments have to process the so-called “biological big data” that is now
reaching the size of Terabytes and Petabytes. To process this huge amount of data …

Peptides as a strategy against biofilm-forming microorganisms: structure-activity relationship perspectives

RG Von Borowski, AJ Macedo, SCB Gnoatto - European Journal of …, 2018 - Elsevier
Biofilm forming microorganisms substantially enhance their virulence and drug resistance
causing and alternatives are need to combat this health problem. In this context, peptides …

Using SEQUEST with theoretically complete sequence databases

RG Sadygov - Journal of the American Society for Mass …, 2015 - ACS Publications
SEQUEST has long been used to identify peptides/proteins from their tandem mass spectra
and protein sequence databases. The algorithm has proven to be hugely successful for its …

Improved mass defect model for theoretical tryptic peptides

I Mitra, AV Nefedov, AR Brasier… - Analytical chemistry, 2012 - ACS Publications
Improvements in the mass accuracy and resolution of mass spectrometers have greatly
aided mass spectrometry-based proteomics in profiling complex biological mixtures. With …

Enumeration of virtual libraries of combinatorial modular macrocyclic (bracelet, necklace) architectures and their linear counterparts

M Taniguchi, H Du, JS Lindsey - Journal of chemical information …, 2013 - ACS Publications
A wide variety of cyclic molecular architectures are built of modular subunits and can be
formed combinatorially. The mathematics for enumeration of such objects is well-developed …

Investigation of scrambled ions in tandem mass spectra, part 2. On the influence of the ions on peptide identification

N Dong, Y Liang, L Yi, H Lu - Journal of The American Society for …, 2013 - ACS Publications
A comprehensive investigation was performed to understand the influence of sequence
scrambling in peptide ions on peptide identification results. To achieve this, four tandem …

Use of singular value decomposition analysis to differentiate phosphorylated precursors in strong cation exchange fractions

RG Sadygov - Electrophoresis, 2014 - Wiley Online Library
We studied the use of peak deviations (PDs) for application in phosphoproteomics. Due to
the differences in the mass defects, the PDs of samples containing mixtures of …

Early stages of phylogenesis of peptide regulation

AT Mar'Yanovich - Journal of Evolutionary Biochemistry and Physiology, 2014 - Springer
Data of literature and results of own studies formed the basis for the author's concepts
according to which:(1) elements of the system of peptide regulation are exclusively peptides …

Ранние этапы филогенеза пептидной регуляции

АТ Марьянович - Журнал эволюционной биохимии и физиологии, 2014 - elibrary.ru
Данные литературы и результаты собственных исследований легли в основу
концепции автора, согласно которой:(1) элементами системы пептидной регуляции …

Computerized Amino Acid Composition Enumeration

RG Sadygov, I Mitra - US Patent App. 13/396,340, 2012 - Google Patents
A computerized method and apparatus for enumerating one or more amino acid
compositions is disclosed that provides one or more processors, a data storage …