Structure and dynamics of interfacial peptides and proteins from vibrational sum-frequency generation spectroscopy

S Hosseinpour, SJ Roeters, M Bonn, W Peukert… - Chemical …, 2020 - ACS Publications
Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

Probing orientations and conformations of peptides and proteins at buried interfaces

W Guo, T Lu, Z Gandhi, Z Chen - The Journal of Physical …, 2021 - ACS Publications
Molecular structures of peptides/proteins at interfaces determine their interfacial properties,
which play important roles in many applications. It is difficult to probe interfacial …

Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions

D Maltseva, S Chatterjee, CC Yu, M Brzezinski… - Nature …, 2023 - nature.com
Biomolecular condensates, protein-rich and dynamic membrane-less organelles, play
critical roles in a range of subcellular processes, including membrane trafficking and …

Elevated concentrations cause upright alpha-synuclein conformation at lipid interfaces

SJ Roeters, K Strunge, KB Pedersen… - Nature …, 2023 - nature.com
The amyloid aggregation of α-synuclein (α S), related to Parkinson's disease, can be
catalyzed by lipid membranes. Despite the importance of lipid surfaces, the 3D-structure and …

Detecting interplay of chirality, water, and interfaces for elucidating biological functions

ECY Yan, EA Perets, D Konstantinovsky… - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Chemists have long been fascinated by chirality, water, and interfaces, making
tremendous progress in each research area. However, the chemistry emerging from the …

Lipid-driven condensation and interfacial ordering of FUS

S Chatterjee, D Maltseva, Y Kan, E Hosseini… - Science …, 2022 - science.org
Protein condensation into liquid-like structures is critical for cellular compartmentalization,
RNA processing, and stress response. Research on protein condensation has primarily …

Effect of pH and urea on the proteins secondary structure at the water/air interface and in solution

T Guckeisen, S Hosseinpour, W Peukert - Journal of Colloid and Interface …, 2021 - Elsevier
Hypothesis The secondary structure of proteins affects their functionality and performance in
physiological environments or industrial applications. Change of the solution pH or the …

Direct observation of long-range chirality transfer in a self-assembled supramolecular monolayer at interface in situ

Y Zhang, X Qin, X Zhu, M Liu, Y Guo… - Nature Communications, 2022 - nature.com
Due to the interest in the origin of life and the need to synthesize new functional materials,
the study of the origin of chirality has been given significant attention. The mechanism of …

Determination of protein conformation and orientation at buried solid/liquid interfaces

W Guo, T Lu, R Crisci, S Nagao, T Wei, Z Chen - Chemical Science, 2023 - pubs.rsc.org
Protein structures at solid/liquid interfaces mediate interfacial protein functions, which are
important for many applications. It is difficult to probe interfacial protein structures at buried …

Role of Water in CaCO3 Biomineralization

H Lu, YC Huang, J Hunger, D Gebauer… - Journal of the …, 2021 - ACS Publications
Biomineralization occurs in aqueous environments. Despite the ubiquity and relevance of
CaCO3 biomineralization, the role of water in the biomineralization process has remained …