Developing sensory circuits exhibit different patterns of spontaneous activity, patterns that
are related to the construction and refinement of functional networks. During the …

The 24 h (circadian) timing system develops in mammals during the perinatal period. It
carries out the essential task of anticipating daily recurring environmental changes to identify …

To test the hypothesized crucial role of microglia in the developmental refinement of neural
circuitry, we depleted microglia from mice of both sexes with PLX5622 and examined the …

The ability of the adult mammalian brain to compensate for neuronal loss caused by injury or
disease is very limited. Transplantation aims to replace lost neurons, but the extent to which …

A comprehensive developmental timeline of activity in the mouse cortex in vivo is lacking.
Understanding the activity changes that accompany synapse and circuit formation is …

The orbitofrontal cortex (OFC) encodes expected outcomes and plays a critical role in
flexible, outcome-guided behavior. The OFC projects to primary visual cortex (V1), yet the …

Gamma oscillations are a prominent activity pattern in the cerebral cortex. While gamma
rhythms have been extensively studied in the adult prefrontal cortex in the context of …

γ oscillations (20–80 Hz) are associated with sensory processing, cognition, and memory,
and focused attention in animals and humans. γ activity can arise from several neural …

Visual spatial perception in the mammalian brain occurs through two parallel pathways: one
reaches the primary visual cortex (V1) through the thalamus and another the superior …

Rodent rhythmic whisking behavior matures during a critical period around 2 weeks after
birth. The functional adaptations of neocortical circuitry during this developmental period …