Ischemia/reperfusion (I/R) injury in the skeletal muscle is inevitable in many vascular and
musculoskeletal traumas, diseases, free tissue transfers, and during time-consuming …

Skeletal muscle regeneration following acute injury is a multi-step process involving
complex changes in tissue microenvironment. Macrophages (MPs) are one of the key cell …

Background: Lower limb ischemia-reperfusion injury (IRI-LL) is a common major
complication of orthopedic surgery, especially in elderly patients. It has previously been …

Current methodology described to mimic lower limb ischaemia–reperfusion injury (LL-IRI)
does not accurately define the procedures and pressures exerted to induce and maintain …

Beta-lactam antibiotics are one of the most commonly used drug classes in managing
bacterial infections. However, their use is threatened by the alarming phenomenon of …

Microdialysis techniques have been used to detect hydroxyl radical and superoxide release
into the interstitial space of anaesthetized rat anterior tibialis muscles during a period of …

The effect of allopurinol, superoxide‐dismutase, and hyperbaric oxygen was compared on
axial pattern skin flap survival. An abdominal flap based on the inferior epigastric pedicle …

Background Studies have focused on enhancing flap viability using superoxide dismutase
(SOD), but only a few used SOD from human origin, and most gave the compound …

Selective superoxide dismutase (SOD) mimetics are potentially useful in pathological
conditions in which there is an overproduction of the superoxide anion O2⋅. These …

Objectives: to assess the efficacy of recombinant human manganese superoxide dismutase
(rhMnSOD) in prevention of early and late skeletal muscle ischaemia-reperfusion injury …