The state of melanoma: emergent challenges and opportunities
MB Atkins, C Curiel-Lewandrowski, DE Fisher… - Clinical Cancer …, 2021 - AACR
Five years ago, the Melanoma Research Foundation (MRF) conducted an assessment of the
challenges and opportunities facing the melanoma research community and patients with …
challenges and opportunities facing the melanoma research community and patients with …
Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification
In the 2022 fifth edition of the WHO Classification of Endocrine Tumours and of Central
Nervous System Tumours, pituitary adenomas are reclassified as neuroendocrine tumours …
Nervous System Tumours, pituitary adenomas are reclassified as neuroendocrine tumours …
Overdiagnosis is increasing the carbon footprint of healthcare
Clinical practice varies—some is excellent, delivering high quality care, improving health
outcomes, and representing excellent value for money. But research over the past two …
outcomes, and representing excellent value for money. But research over the past two …
The effect of screening on melanoma incidence and biopsy rates
Background Cutaneous melanomas are common cancers in white‐skinned populations,
and early detection is promoted as a means of reducing morbidity and mortality. There is …
and early detection is promoted as a means of reducing morbidity and mortality. There is …
Co-design of a trustworthy AI system in healthcare: deep learning based skin lesion classifier
This paper documents how an ethically aligned co-design methodology ensures
trustworthiness in the early design phase of an artificial intelligence (AI) system component …
trustworthiness in the early design phase of an artificial intelligence (AI) system component …
Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?
MJ Duffy, EP Diamandis, J Crown - Clinical Chemistry and …, 2021 - degruyter.com
The detection of cancer at an early stage while it is curable by surgical resection is widely
believed to be one of the most effective strategies for reducing cancer mortality. Hence, the …
believed to be one of the most effective strategies for reducing cancer mortality. Hence, the …
Overdiagnosis and overuse of diagnostic and screening tests in low-income and middle-income countries: a scoping review
Objective Overdiagnosis and overuse of healthcare services harm individuals, take
resources that could be used to address underuse, and threaten the sustainability of health …
resources that could be used to address underuse, and threaten the sustainability of health …
Early diagnosis of low-risk papillary thyroid cancer results rather in overtreatment than a better survival
J Krajewska, A Kukulska… - Frontiers in …, 2020 - frontiersin.org
We are witnessing a rapid worldwide increase in the incidence of papillary thyroid
carcinoma (PTC) in the last thirty years. Extensive implementation of cancer screening and …
carcinoma (PTC) in the last thirty years. Extensive implementation of cancer screening and …
How do people understand overtesting and overdiagnosis? Systematic review and meta-synthesis of qualitative research
Rationale The public should be informed about overtesting and overdiagnosis. Diverse
qualitative studies have examined public understandings of this information. A synthesis …
qualitative studies have examined public understandings of this information. A synthesis …
Incidence of in situ vs invasive melanoma: testing the “obligate precursor” hypothesis
Background Melanoma incidence has been rising in populations with predominantly
European ancestry (White), speculated to be partly driven by heightened detection of …
European ancestry (White), speculated to be partly driven by heightened detection of …